Research Technologist I, Molecular Medicine

SickKids; Toronto; On-site; CAD 60,000 - 80,000; Full time

Job summary

A leading children's hospital seeks a Research Technologist I to assist in protein production and laboratory experiments aimed at developing vaccines and antibodies. Ideal candidates will have a background in biochemistry and molecular biology, with a commitment to collaborative research. This role offers the chance to enhance children's health through impactful scientific work.

Benefits

Employee wellness programs

Academic and learning environment

Mentoring programs

Qualifications

• 2+ years of wet lab experience required.
• Experience expressing and purifying proteins for biochemical assays.

Responsibilities

• Execute protein production from mammalian expression systems.
• Develop and optimize experimental methods for in vitro assays.

Skills

Biochemistry

Molecular Biology

In vitro Assay Development

Communication

Education

Bachelor or Masters of Science

Tools

BLI

SPR

ITC

ELISA

Flow Cytometry

Job description

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Research Technologist I, Molecular Medicine

Position Description

Dr. Julien's laboratory at The Hospital for Sick Children Research Institute is looking for a Research Technologist I to assist in executing protein production and laboratory experiments for the development of vaccines and antibodies for the treatment of infectious diseases. We are looking for a driven and enthusiastic scientist with experience in biochemistry, molecular biology, and in vitro assay development who can thrive in a highly collaborative research setting.

Here's What You'll Get To Do:

• Work under the direction of senior staff to execute protein production from mammalian expression system for the generation of antigens and antibodies.
• Develop and / or optimize experimental methods to expand in vitro ligand binding assays.
• Grow your knowledge and technical skill set around the use of vaccines and antibodies for the prevention of infectious diseases.
• Support and collaborate with project team members to meet deliverables and timelines.
• Contribute towards the development of guidelines, procedures and standards.
• Analyze, interpret, and report experimental results in written, verbal or graphical form as required to senior staff and at lab meetings.
  

Here's What You'll Need:

• Bachelor or Masters of Science degree in Biochemistry, Molecular Biology, Cell Biology or Immunology with 2+ years of wet lab experience.
• Experience expressing and purifying proteins for downstream biochemical assays and/or structural biology. High-throughput protein expression is considered an asset.
• Experience with one of E. coli, yeast, insect, and/or mammalian protein expression systems is required, while experience with mammalian protein expression systems (e.g. HEK 293, CHO) is preferred.
• Experience performing in vitro binding assays such as BLI, SPR, ITC, and/or ELISA. Experience with flow cytometry is considered an asset.
• Ability to function in a timeline-driven, dynamic environment, and to adapt to new techniques and protocols.
• Demonstrated competency in written and verbal communications.
• Ability to work independently as well as part of a team.
• Committed to continuous learning and improvement.
• Demonstrated ability to participate in collaborative and productive scientific projects.
• A commitment to understanding and aiding in the pursuit of equity, diversity and inclusion objectives.

Here's What You'll Love:

• Enhancing children's health and changing the lives of children and their families every day
• A focus on employee wellness with our new Staff Health and Well-being Strategy. Self-care helps us support others
• A hospital that welcomes and focuses on Equity, Diversity, and Inclusion.
• The opportunity to make an impact. Regardless of your role or professional interest, you'll be making a difference at SickKids and contributing to our vision of Healthier Children. A Better World.
• An academic and learning environment, awards and bursaries, mentoring programs, and a focus on continuous improvement.
  

Employment Type: Full-time temporary 1 year contract, 1.0 FTE

How to Apply?
Upload your CV and a letter of intent when applying before May23rd, 2025. Successful candidates will be notified for interviews, at which time two letters of references will also be required.

About Us
Dr. Julien's laboratory focuses on the molecular characterization of antibodies by studies of their interactions with cell surface receptors in therapeutic development, and with pathogens guiding vaccine design primarily against Plasmodium falciparum malaria, HIV-1 and COVID-19. Dr. Julien's laboratory is located in the Molecular Medicine Program of The Peter Gilgan Centre for Research and Learning at SickKids, a 21-story, 750,000 square-foot facility that incorporates an open-concept design, state-of-the-art research facilities, and collaborative workspaces.
As a member of the SickKids community, you will become part of a world-renowned organization dedicated to fulfilling a vision of Healthier Children, A Better World. For over 135 years, SickKids has worked hard to make the world a better place for children and their families. Each day, people around the organization are doing meaningful work that directly, and often indirectly, benefits children in Canada and around the world.

Our Commitment to Diversity

The children and families we care for are from a variety of communities, and so are our employees. We welcome and encourage everyone to join our organization and be part of our team.

When requested, SickKids will provide access and inclusion supports to eligible candidates to support their full engagement during the interview and assessment process. Information received related to access or inclusion will be addressed confidentially.

Thank you for your interest in joining SickKids. Only those applicants selected for an interview will be contacted. In accordance with our Hospital policy, employment at SickKids is conditional upon the Hospital's receipt of all necessary documentation.

How to Apply

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