Research Technician / Technicien(ne) en Recherche - Evening Shift (2PM-10PM)

Thryv Therapeutics Inc.; Montreal; On-site; CAD 42,000 - 64,000; Full time

Job summary

Thryv Therapeutics Inc. invites applications for a motivated research technician to assist in biochemical and cellular assays, mammalian cell culture, and general lab operations at the CQIB facility in Laval, Quebec.

This full-time role supports drug discovery activities and cross-functional collaboration with a multidisciplinary team. The ideal candidate is a current graduate student or recent graduate in a life sciences field, with hands-on lab experience and strong attention to detail.

Qualifications

• Current graduate student, recent graduate, or undergraduate student in biotechnology, biology, biochemistry, pharmacology, life sciences, or related discipline.
• Undergraduate degree with hands-on experience in biotech, pharma, CRO or industrial lab environment.

Responsibilities

• Support biochemical and cellular assays, including compound screening and SAR analysis.
• Perform routine mammalian cell culture with aseptic technique.
• Execute established protocols and maintain accurate lab records.
• Monitor assay quality and communicate deviations promptly.
• Maintain inventory and storage of supplies; assist with ordering.

Skills

Mammalian cell culture

Biochemical assays

Multi-well plate work

Pipetting

CRISPR knowledge

iPSC culture

Lab documentation

Excel/GraphPad

Education

Undergraduate degree in biotechnology or related

Graduate student preferred

Tools

GraphPad Prism

MS Excel

Electronic lab notebook

Job description

Thryv Therapeutics is looking for a motivated research technician to support the execution of biochemical and cellular assays, mammalian cell culture, and laboratory operations in our biotechnology R&D laboratory located at the Centre québécois d’innovation en biotechnologie (CQIB) in Laval, Quebec.

This full-time position will support a range of drug discovery and research activities, including compound screening, as well as biochemical and cellular potency assays to determine structure-activity relationships (SAR). The successful candidate will work closely with a multidisciplinary team to develop new precision medicines.

KEY RESPONSIBILITIES

• Support biochemical and cellular assays for a range of research activities, including compound screening, potency testing, structure-activity relationship (SAR) analysis, and other project-specific activities.
• Perform routine mammalian cell culture activities and prepare the necessary cells, reagents, compounds, and assay materials for planned experiments.
• Execute established experimental protocols and maintain complete, accurate, and up-to-date laboratory documentation.
• Monitor assay quality, cell health, and experimental controls; promptly communicate any deviations, equipment issues, or unexpected results.
• Maintain laboratory inventory, support ordering and receiving, and ensure proper storage and organization of laboratory supplies.
• Perform routine equipment checks and maintain a safe, clean, organized, and operationally laboratory environment.
• Participate in daily shift handoffs with scientists and complete end-of-shift laboratory closing procedures.
• Follow all applicable SOPs, biosafety, chemical safety, data integrity, and applicable CQIB requirements.
• Provide support to other members of the research team.

QUALIFICATIONS

REQUIRED EDUCATION, EXPERIENCE:

• Current graduate student, recent graduate, or undergraduate student in biotechnology, biology, biochemistry, pharmacology, life sciences, laboratory techniques, or a related scientific discipline.
• Or an undergraduate university degree in a relevant scientific field, accompanied by prior hands-on experience in a biotechnology, pharmaceutical, CRO, or another industrial laboratory environment.

TECHNICAL KNOWLEDGE, SKILLS:

• Demonstrated hands-on experience or training in mammalian cell culture, specifically in aseptic technique, cell maintenance, cell counting, and cell seeding.
• Experience or familiarity with biochemical and/or cellular assays, multi-well plate workflows (96-well and/or 384-well plates), pipetting, serial dilutions, reagent preparation, and basic assay controls.
• Familiarity with Western blotting, PCR, and CRISPR-based gene-editing techniques is a plus, but is not required.
• Familiarity with induced pluripotent stem cell (iPSC) culture, maintenance, and differentiation is a plus, but is not required.
• Familiarity with laboratory equipment such as biosafety cabinets, CO₂ incubators, centrifuges, plate readers, microscopes, cell counters, and multichannel pipettes.
• Experience with electronic laboratory notebooks, inventory systems, Microsoft Excel, GraphPad Prism, or comparable laboratory data-management tools.
• Familiarity with the responsible use of AI tools to support research and documentation, including verification of AI-generated outputs, protection of confidential information, and adherence to company policies, is a plus but is not required.
• Strong attention to detail, organizational skills, and the ability to accurately follow established protocols.
• Ability to maintain clear, accurate, and timely laboratory records.

NON-TECHNICAL KNOWLEDGE AND SKILLS:

• Meticulous attention to detail, particularly when conducting experiments.
• Operates with a sense of urgency and perseverance to achieve results.
• Ability and enthusiasm to work in a cross-functional team environment.
• Excellent oral/written communication, interpersonal, and organizational skills.
• Self-motivated with the ability to work independently with minimal supervision.
• Adapts quickly to changes in project scope, direction, and timelines by being receptive and agile in learning new techniques or approaches.
• Ability to work effectively and independently within a scientific team.
• Availability to work on-site in Laval, Monday to Friday from 2:00 PM to 10:00 PM, and/or occasionally on weekends.
• French-language skills. English-language skills are an asset where required for scientific literature, protocols, equipment manuals, supplier documentation, or collaboration with external partners.
• Legal authorization to work in Canada is required.

TRAVEL

Travel is not required, but presence in the laboratory located on boulevard Cartier in Laval, Quebec, is required.

Thryv Therapeutics Inc. is a privately owned clinical-stage biopharmaceutical company, based in Montreal, Quebec, with a laboratory located in Laval, Quebec. For more information, please visit www.thryvtrx.ca.