Principal Scientist, Bioanalytical R&D – LC-MS/MS Method Development

Groom & Associés / Associates; Laval (administrative region); On-site; CAD 120,000 - 180,000; Full time

Benefits offered by this job

Group insurance

RRSP matching up to 3%

Vacation 3–4 weeks

Personal/sick days 7

Job summary

Groom & Associates invites applications from an experienced Principal Scientist to lead LC-MS/MS bioanalytical R&D in a GLP-compliant laboratory and to oversee a specialized R&D team.

The role combines leadership with hands-on method development for small and large molecules, collaboration with operations and commercial teams, and ongoing scientific strategy development. The position is full-time and based in Laval, QC.

Qualifications

• Master's degree or Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or related field.
• 8–10 years of LC-MS/MS bioanalytical laboratory experience in a GLP environment.
• At least 5 years in Research & Development with bioanalytical method development.
• Advanced LC-MS/MS and analytical chemistry expertise.
• Experience with small and/or large molecules and GLP compliance.
• Proven ability to lead projects and teams across disciplines.

Responsibilities

• Lead bioanalytical R&D activities, including LC-MS/MS method development for small and large molecules.
• Develop innovative analytical methodologies and oversee client method transfers for GLP validation or sponsor submissions.
• Review and approve R&D reports, methods, and data to ensure scientific excellence and integrity.
• Lead, mentor, and develop a specialized R&D team and manage resource allocation.
• Collaborate with GLP Operations, Method Validation, and Mass Spectrometry teams for project execution.
• Identify opportunities to improve laboratory efficiency and capabilities.

Skills

LC-MS/MS bioanalysis

Leadership

Project oversight

Analytical chemistry

GLP compliance

Team leadership

Client collaboration

Problem solving

Education

Master's or PhD in Chemistry/Biochemistry/Pharmaceutical Sciences

Tools

LC-MS/MS instrumentation

Bioanalytical method development

Job description

Principal Scientist, Bioanalytical R&D – LC-MS/MS Method Development

Employment Type: Full-time, Permanent

About the Opportunity

Groom & Associés is currently partnering with an established organization in the pharmaceutical and biotechnology research sector to recruit an experienced Principal Scientist, Bioanalytical R&D – LC-MS/MS.

This is an exciting opportunity for an accomplished scientific professional to take a leadership role within a GLP-compliant bioanalytical laboratory, overseeing method development, driving scientific innovation, and leading a specialized Research & Development team.

The successful candidate will combine deep technical expertise in LC-MS/MS bioanalysis with strong scientific leadership, project oversight, and the ability to collaborate across research, operations, and commercial functions.

Key Responsibilities

Scientific Leadership & Method Development

• Lead bioanalytical R&D activities, including LC-MS/MS method development for small and large therapeutic molecules.
• Develop innovative analytical methodologies and oversee the implementation and verification of client methods.
• Serve as the principal scientific expert for LC-MS/MS method development and complex analytical challenges.
• Review and approve R&D reports, analytical methods, and scientific data prior to transfer for GLP validation or submission to sponsors.
• Ensure scientific excellence, data integrity, and compliance with applicable GLP standards and internal procedures.
• Stay current with emerging technologies, regulatory developments, and industry best practices.

Team Leadership & Operational Collaboration

• Lead, mentor, and develop a specialized team of R&D scientists.
• Oversee departmental activities, project priorities, resource allocation, and scientific deliverables.
• Support recruitment, onboarding, and professional development within the R&D department.
• Collaborate closely with GLP Operations, Method Validation, and Mass Spectrometry teams to ensure successful project execution.
• Identify opportunities to improve laboratory efficiency, scientific capabilities, and departmental performance.

Scientific Strategy & Client Collaboration

• Act as a key scientific resource for internal stakeholders and external clients.
• Provide technical expertise during project feasibility assessments, scientific discussions, and proposal development.
• Partner with Business Development and commercial teams to evaluate new opportunities, project timelines, and technical requirements.
• Contribute to project quotations, resource estimates, and scientific budget planning.
• Support strategic scientific partnerships and represent the organization at relevant industry events and conferences.

Qualifications & Experience

• Master's degree or Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related scientific discipline.
• Minimum 8–10 years of experience in an LC-MS/MS bioanalytical laboratory operating within a GLP-compliant environment.
• At least 5 years of experience in Research & Development, with significant involvement in bioanalytical method development.
• Advanced technical expertise in LC-MS/MS, analytical chemistry, and bioanalytical assay development.
• Experience working with small molecules and/or large therapeutic molecules.
• Strong understanding of GLP requirements, method validation, and analytical data integrity.
• Demonstrated ability to lead scientific projects, resolve complex technical challenges, and collaborate with multidisciplinary teams.
• Previous team leadership or scientific management experience is strongly valued.
• Excellent organizational, problem-solving, and stakeholder management skills.

What We Offer

• 3–4 weeks of vacation, depending on experience.
• 7 personal/sick days annually.
• Group insurance following the probationary period.
• Employer RRSP matching contributions of up to 3%.
• Monday-to-Friday schedule, 36.25 hours per week.
• Opportunity to lead scientific innovation within a specialized bioanalytical research environment.

Why Consider This Opportunity?

This position offers the opportunity to play an influential role in shaping scientific strategy, developing innovative bioanalytical methodologies, and contributing to the growth of an established research organization.

For an experienced LC-MS/MS scientist seeking greater scientific ownership, team leadership responsibilities, and exposure to complex pharmaceutical and biotechnology research programs, this represents an excellent next step.

Interested in Learning More?

Groom & Associés invites qualified candidates to apply directly through LinkedIn.

All applications will be handled with professionalism and confidentiality.