Associate Scientist – Digital Discovery: Antibody Bioinformatics

Amgen Inc. (IR); Burnaby; On-site; CAD 92,000 - 125,000; Full time

Benefits offered by this job

Equal opportunity employer

Job summary

Amgen Inc. (IR) in Canada is seeking an Associate Scientist – Digital Discovery: Antibody Bioinformatics to join a collaborative team that combines experimental biology with bioinformatics and data analysis for biologics discovery.

You will run computational workflows, assess sequencing data quality, and develop scripts to automate BCR‑Seq analyses, while organizing and integrating data across discovery programs with wet‑lab and computational scientists.

Qualifications

• Master’s degree with 1+ year relevant experience or Bachelor’s with 3+ years in Biological Sciences, Biochemistry, Molecular Biology, Immunology, Bioinformatics, Computational Biology, or related field.
• Hands‑on wet‑lab or experimental research in molecular biology, immunology, biologics or antibody discovery, genomics, NGS, protein characterization, or related life‑science discipline.
• Training or experience in bioinformatics, computational biology, scientific informatics, or biological data analysis.

Responsibilities

• Run established antibody discovery computational workflows, assess sequencing and data quality, and support downstream analysis of antibody repertoires and candidate sequences.
• Develop R and/or Python scripts, analytical tools, reports, and visualizations to automate downstream BCR‑Seq analyses and enable scientists to explore, interpret, and communicate discovery results.
• Organize, curate, and integrate BCR‑Seq, antibody screening, and associated experimental data and metadata to support downstream analysis and reuse across antibody discovery programs.
• Apply hands‑on knowledge of molecular biology, immunology, biologics discovery, genomics, NGS, and related laboratory workflows to interpret data within its experimental context.
• Communicate analytical findings and recommendations through clear visualizations, concise scientific summaries, and collaborative problem‑solving.

Job description

Career Category Scientific Job Description

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Associate Scientist – Digital Discovery: Antibody Bioinformatics

What you will do Let’s do this. Let’s change the world. In this vital role, you will join a collaborative Digital Discovery team of scientists who combine experimental biology with bioinformatics and data analysis to improve how biologics discovery data are generated, captured, analyzed, and reused. This bench‑proximal computational role is designed for a scientist with hands‑on wet‑lab or experimental training and demonstrated experience or training in bioinformatics, computational biology, or biological data analysis. Working alongside experimental and computational colleagues, you will help turn complex biological data into reproducible, analysis‑ready information that supports discovery decisions. You will apply biological context to data quality and interpretation, develop or adapt practical analytical tools, and strengthen the connection between laboratory workflows, biological data, and downstream analysis.

Bioinformatics & Data Analysis Run established antibody discovery computational workflows, assess sequencing and data quality, and support downstream analysis of antibody repertoires and candidate sequences. Analyze BCR repertoire, NGS, single‑cell, protein, and associated antibody discovery datasets to characterize sequence diversity, identify antibody candidates, and support discovery decisions, with guidance from senior team members as appropriate. Develop R and/or Python scripts, analytical tools, reports, and visualizations to automate downstream BCR‑Seq analyses and enable scientists to explore, interpret, and communicate discovery results.

Biological Data Integration & Curation Organize, curate, and integrate BCR‑Seq, antibody screening, and associated experimental data and metadata to support downstream analysis, data mining, and reuse across antibody discovery programs. Work with wet‑lab scientists to ensure sample, sequencing, and antibody discovery data are captured, connected, and structured to support downstream analysis and traceability, including within platforms such as Benchling.

Experimental Partnership & Team Collaboration Apply hands‑on knowledge of molecular biology, immunology, biologics discovery, genomics, NGS, and related laboratory workflows to interpret data within its experimental context. Partner with wet‑lab and computational scientists to investigate data‑quality issues, improve experimental‑to‑computational handoffs, and help ensure experiments generate robust, analysis‑ready data. Communicate analytical findings and recommendations through clear visualizations, concise scientific summaries, and collaborative problem‑solving.

What we expect of you

Basic Qualifications:

• - Master’s degree and 1+ year of relevant experience OR Bachelor’s degree and 3+ years of relevant experience in Biological Sciences, Biochemistry, Molecular Biology, Immunology, Bioinformatics, Computational Biology, or a related field.

Preferred Qualifications:

• - Hands‑on wet‑lab or experimental research experience in molecular biology, immunology, biologics or antibody discovery, genomics, NGS, protein characterization, or a related life‑science discipline.
• - Demonstrated training or experience in bioinformatics, computational biology, scientific informatics, or biological data analysis through coursework, research projects, internships, or professional experience.
• - Working knowledge of R and/or Python for biological data analysis, visualization, and scripting; experience with SQL is a plus.
• - Experience working with complex experimental datasets and associated metadata, including data curation, integration, quality control, and documentation.
• - Exposure to NGS, immune repertoire, single‑cell, flow cytometry, or other high‑dimensional biological datasets; familiarity with tools such as Cell Ranger, Seurat/Scanpy, FlowJo, Bioconductor, or comparable platforms is a plus.
• - Familiarity with Linux/command‑line environments, reproducible analysis practices, cloud/HPC environments, and/or laboratory informatics systems such as Benchling, ELNs, or LIMS.
• - Strong communication, organization, and collaboration skills, with an interest in working across experimental and computational disciplines.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

Amgen is proud to have been recognized as one of LinkedIn Top 25 Companies in Canada for career growth.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Salary Range 92,476.60 CAD - 125,115.40 CAD

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people’s lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world’s leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.