Scientist – Molecular Analytics (1 Year Contract)

Amgen; Burnaby; On-site; CAD 85,000 - 120,000; Part time

Job summary

Amgen in Burnaby, BC is seeking a highly motivated Scientist – Molecular Analytics to support early phase discovery programs. You will work within BEAM to characterize reagents and therapeutic candidates using advanced MS and LC-MS methods.

The role involves collaboration with cross-functional teams, method development, and training of lab staff. A PhD or equivalent is desirable, with strong data analysis and reporting skills, on-site in Burnaby.

Qualifications

• Bachelor/Master/PhD with lab experience in analytical chemistry or biochemistry.
• Experience with mass spectrometry and chromatography techniques.
• PhD or equivalent research training is a plus.

Responsibilities

• Maintain and oversee mass spectrometry and liquid chromatography instrumentation and lab processes.
• Perform intact and sub-unit protein mass analysis to confirm protein identity.
• Perform peptide analysis to confirm sequence and modifications.
• Train staff on sample prep and instrument use, and troubleshoot software and data.
• Develop, transfer, and qualify new LC-MS/LC-MS/MS methods.
• Analyze data with automated workflows and maintain organized records.

Skills

Mass spectrometry

LC-MS

Protein analytics

Data analysis

Laboratory skills

Team collaboration

Education

Bachelor’s Degree in Chemistry/Biochemistry/Molecular and Cellular Biology

Master’s Degree in a related field

PhD

Tools

QTOF mass spectrometer

Orbitrap mass spectrometer

UPLC

MassHunter

Proteome Discoverer

Xcalibur

Byos

Job description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Role: Scientist – Molecular Analytics

Reports to: Principal Scientist

Location: Burnaby, British Columbia (Onsite)

Type: 1 year contract, possibility of extension

What you will do:

Let’s do this. Let’s change the world. In this vital role you will join the Biologics Engineering with Advanced Mass Spectrometry (BEAM) team at our Research facility in Burnaby, BC, Canada.

We are looking for a highly motivated scientist to work with cross functional teams to characterize both reagent and therapeutic protein candidates using various analytical techniques to support Amgen’s early phase discovery programs.

The successful candidate will work in a highly collaborative team environment and contribute independently to diverse functions depending upon project needs and priority.

• Maintain and oversee mass spectrometry and liquid chromatography instrumentation and laboratory processes
• Perform intact and sub‑unit protein mass analysis to confirm protein identity supporting a variety of large molecules
• Perform peptide analysis to confirm sequence and protein modifications
• Train protein biochemistry staff on sample preparation and sample submission and assist/troubleshoot with instrumentation, software and data interpretation
• Participate in the design, development, implementation, method transfer and qualification of novel LC‑MS and LC‑MS/MS methods
• Analyze and interpret data using automated workflows and maintain file organization

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a person with these qualifications

Basic Qualifications:

• Bachelor’s Degree in Chemistry, Biochemistry, Molecular and Cellular Biology or a related discipline and 5 years of scientific laboratory experience.OR
• Master’s Degree in a closely related scientific discipline and 2+ years of laboratory experienceORli>
• PhD

and

• Mass Spectrometry and Chromatography experience

Preferred Qualifications:

• Training in analytical chemistry/biochemistry, including proficiency in operation of QTOF and Orbitrap mass spectrometers and UPLC instrumentation with 5+ years general laboratory experience. Prior experience supporting users is highly desired
• 2+ years of hands‑on experience in protein analytics. Experience with intact, sub‑unit protein mass and peptide analysis is preferred
• Familiarity with common LC‑MS data acquisition and analysis software such as MassHunter, Byos, Proteome Discoverer, MASCOT, Xcalibur, etc. is desired
• Experience with handling and analyzing large datasets is an asset
• Ability to follow established laboratory protocols and adhere to data standards; attention to detail and careful execution of laboratory tasks are essential
• Strong oral and written communication skills and organizational skills
• Proficient in Microsoft Excel, Word, PowerPoint; experience with electronic notebooks
• Must work well in a team, adaptable, fast paced environment
• Resides in the Greater Vancouver Area

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well‑being.

Amgen is proud to have been recognized as one of LinkedIn Top 25 Companies in Canada for career growth.

In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.