Senior Oncology Safety & Risk Director (Global)

GSK; Waver; On-site; EUR 141,000 - 235,000; Full time

Job summary

GSK’s Oncology Safety leadership role seeks a Scientific Director to guide safety evaluation and risk management across clinical development, shaping safety strategy and protecting patients globally. This role partners with Safety Physicians and cross-functional teams to ensure high-quality decision-making, timely risk mitigation, and robust regulatory submissions.

The position emphasizes mentorship within a global matrix, contributing to long-term safety strategies across multiple therapeutic

Qualifications

• Degree in a health or life sciences discipline (e.g., Bachelor of Science, PharmD, MD, PhD, or equivalent).
• Extensive experience in pharmacovigilance, drug safety, or related safety evaluation role in the pharmaceutical or biotech industry.
• Practical experience in signal detection, safety surveillance and risk management across clinical development and post-marketing.
• Knowledge of global pharmacovigilance requirements and drug development processes.
• Strong clinical or scientific judgement with experience interpreting clinical and safety data.

Responsibilities

• Lead pharmacovigilance activities and risk mitigation strategies for assigned oncology assets and clinical trials
• Drive the evaluation and interpretation of safety data, including signal detection and assessment
• Develop strategic approaches for safety issue evaluation within clinical development programs
• Contribute to safety components of global regulatory submissions (e.g., INDs, DSURs, IBs)
• Perform literature review, clinical data synthesis, and integrated safety analyses to inform decision-making
• Ensure high-quality, timely delivery of outputs while managing multiple priorities
• Represent Safety Evaluation & Risk Management on Clinical Matrix and Project Teams
• Lead cross-functional efforts to address urgent and complex product safety issues
• Partner closely with Safety Physicians and stakeholders to prepare and present at Safety Review Team meetings
• Escalate emerging safety issues to senior leadership and governance bodies as appropriate
• Build strong working relationships and effectively lead within a global matrix environment
• Mentor and coach junior team members as applicable
• Present safety recommendations and emerging risks to senior governance committees with clarity and impact
• Represent GSK in interactions with regulatory authorities, external experts, and partners
• Apply strategic thinking to evaluate internal and external factors influencing safety decisions
• Contribute to long-term safety and clinical development strategies
• Drive continuous improvement by introducing innovative approaches to safety evaluation and processes
• Communicate complex scientific information effectively to diverse audiences

Education

Degree in a health or life sciences discipline (e.g., Bachelor of Science, PharmD, MD, PhD, or equivalent).

Advanced degree (PharmD, PhD, MD) or equivalent clinical qualification.

Job description

GSK’s Oncology Safety leadership role seeks a Scientific Director to guide safety evaluation and risk management across clinical development, shaping safety strategy and protecting patients globally. This role partners with Safety Physicians and cross-functional teams to ensure high-quality decision-making, timely risk mitigation, and robust regulatory submissions.

The position emphasizes mentorship within a global matrix, contributing to long-term safety strategies across multiple therapeutic