Principal Statistical Methodologist

UCB; Eigenbrakel; Hybride; EUR 70 000 - 90 000; Plein temps

Avantages offerts par ce poste

Hybrid-first work approach

Résumé du poste

UCB, based in Braine l'Alleud, Belgium, is seeking a Principal Statistical Methodologist to join our Statistical Innovation team. This role involves providing expert statistical consultation on clinical trial design and implementing advanced statistical methods while collaborating across functional teams.

The ideal candidate will have strong statistical programming skills, a doctoral degree in a relevant field, and experience in biostatistics within the pharmaceutical industry. This position offers a hybrid-first work model allowing for flexibility in working remotely.

Qualifications

• 3+ years of experience in biostatistics within the pharmaceutical industry.
• Expertise in innovative trial design.
• Strong knowledge of ICH guidelines.

Responsabilités

• Provide statistical consultation on clinical trial design and analysis.
• Develop and implement innovative statistical approaches.
• Run advanced analyses and simulations.
• Communicate complex quantitative topics clearly.
• Deliver training on advanced statistical concepts.

Connaissances

Statistical programming (R preferred)

Advanced statistical methods

Clinical trial design and analysis

Causal inference and estimands

Formation

Doctoral degree in statistics, mathematics or related field

Description du poste

About The Role

We are looking for a Principal Statistical Methodologist who is curious, collaborative, and strategic to join our Statistical Innovation team within Biometric and Data Sciences (BDS), based in Braine l'Alleud (Belgium).

You will help shape how evidence is generated and communicated across the drug development lifecycle—from early clinical development to regulatory approval and lifecycle work. You will provide expert statistical consultation on trial design and analysis, develop and apply advanced methods, and translate complex quantitative concepts into clear insights for cross-functional partners. You will also contribute to scientific communications and external collaboration through publications and industry initiatives.

Who You Will Work With

You will be part of a team that provides statistical consultancy across therapy areas and development stages, partnering closely with colleagues in clinical development, regulatory strategy, data science, and medical affairs. The team values curiosity, problem solving, practical innovation, clear communication, and collaboration—bringing novel statistical approaches into real study decisions and sharing learnings with the wider scientific community.

What You Will Do

• Provide statistical consultation on clinical trial design and analysis across multiple development stages and therapy areas.
• Develop and implement innovative statistical approaches, including model-based methods using frequentist and Bayesian techniques.
• Run or guide advanced analyses and simulations to inform design options, sample size, and power trade-offs.
• Communicate complex quantitative topics clearly using visuals, simulations, and plain language for diverse audiences.
• Contribute to internal learning by delivering training on advanced statistical concepts for non-statisticians and statisticians.
• Contribute to the group’s external profile through scientific publications, conference presentations, and participation in cross-industry initiatives and working groups.

Requirements

• Doctoral degree in statistics, mathematics, or a closely related scientific discipline.
• 3+ years of experience working in biostatistics within the pharmaceutical industry. Experience in statistical methodology for clinical development (early to late stage) is an advantage.
• Expertise in advanced statistical methods and innovative trial design; experience with causal inference and estimands is an advantage.
• Strong statistical programming skills (R preferred; equivalent tools considered).
• Sound knowledge of ICH guidelines and understanding of regulatory requirements from major health authorities.
• Ability to work effectively with autonomy, manage multiple priorities, and deliver timely, high-quality outputs.

Benefits

Hybrid-first approach: 40% of your time may be spent in the office, with flexibility to work remotely.

Equal Opportunity Employer

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.