Principal Data Platform Architect

CluePoints SA; Belgique; Hybrid; EUR 120,000 - 180,000; Full time

Benefits offered by this job

Health Insurance

Mobility Budget

Group Pension Plan

Meal Vouchers

Eco Vouchers

Hybrid work model

Job summary

CluePoints is seeking a Principal Architect to join our Data Layer squad and contribute to our mission of transforming clinical research through data-driven insights. This is a hands-on, player-coach role where you’ll own the design of the data layer and build it with the squad.

You’ll report to our GM, with a dotted line to the VP Engineering. You will define a metadata-driven schema with a stable spine, build a semantic tier mapping study fields to concepts, and deliver a versioned, auditable

Qualifications

• Own the design of the CluePoints data layer and build it hands-on, writing production code alongside the squad.
• Design a metadata-driven schema with a stable spine that absorbs change without breaking the applications built on it.
• Build a semantic tier that maps study fields to concepts, keeping structure and meaning cleanly separate.
• Deliver a versioned, auditable query interface for our applications, with lineage and attributable change built in.
• Set the squad’s engineering and AI-first practices, using AI tools with clear verification and evaluation.
• Coach engineers through code and design, and partner with our GM and VP Engineering on direction.

Responsibilities

• Own the design of the CluePoints data layer and build it hands-on, writing production code alongside the squad.
• Design a metadata-driven schema with a stable spine that absorbs change without breaking the applications built on it.
• Build a semantic tier that maps study fields to concepts, keeping structure and meaning cleanly separate.
• Deliver a versioned, auditable query interface for our applications, with lineage and attributable change built in.
• Set the squad’s engineering and AI-first practices, using AI tools with clear verification and evaluation.
• Coach engineers through code and design, and partner with our GM and VP Engineering on direction.

Skills

Hands-on coding

System design

Mentorship

AI-first leadership

Technical leadership

Tools

CDISC

FHIR

OMOP

ODM

OpenLineage

DataHub

Iceberg

HAPI FHIR

OHDSI

Multi-tenant SaaS

Job description

At CluePoints, we’re redefining how clinical trials are run. As the premier provider of Risk-Based Quality Management (RBQM) and Data Quality Oversight software, we harness advanced statistics, artificial intelligence, and machine learning to ensure the quality, accuracy, and integrity of clinical trial data, helping life sciences organizations bring safer, more effective treatments to patients faster.

We’re proud to be an ambitious, fast-growing technology scale-up with a dynamic and diverse international team representing more than 20 nationalities. Collaboration, flexibility, and continuous learning are part of our DNA.

At CluePoints, you’ll find a culture where you can grow, make an impact, and have fun along the way. Guided by our values of Care, Passion, and Smart Disruption, we’re united by a shared mission: to create smarter ways to run efficient clinical trials and deliver AI-powered insights that improve human outcomes worldwide.

The Role

We’re looking for a Principal Architect to join our Data Layer squad and contribute to our mission of transforming clinical research through data-driven insights. This is a hands-on, player-coach role: you’ll own the design of the CluePoints data layer and build it with the squad. You’ll report to our GM, with a dotted line to the VP Engineering.

Job requirements

What You’ll Be Doing

• Own the design of the CluePoints data layer and build it hands-on, writing production code alongside the squad.
• Design a metadata-driven schema with a stable spine that absorbs change without breaking the applications built on it.
• Build a semantic tier that maps study fields to concepts, keeping structure and meaning cleanly separate.
• Deliver a versioned, auditable query interface for our applications, with lineage and attributable change built in.
• Set the squad’s engineering and AI-first practices, using AI tools with clear verification and evaluation.
• Coach engineers through code and design, and partner with our GM and VP Engineering on direction.

Nice to Have

• Multi-tenant SaaS experience with strong data segregation.
• Familiarity with clinical data, CDISC, or standards such as FHIR, OMOP, and ODM. We’ll help you with the clinical side.
• Open-source contributions or talks in data lineage, metadata, or health data interoperability (e.g. OpenLineage, DataHub, Iceberg, HAPI FHIR, OHDSI).

Job responsibilities

What You’ll Be Doing

• Own the design of the CluePoints data layer and build it hands-on, writing production code alongside the squad.
• Design a metadata-driven schema with a stable spine that absorbs change without breaking the applications built on it.
• Build a semantic tier that maps study fields to concepts, keeping structure and meaning cleanly separate.
• Deliver a versioned, auditable query interface for our applications, with lineage and attributable change built in.
• Set the squad’s engineering and AI-first practices, using AI tools with clear verification and evaluation.
• Coach engineers through code and design, and partner with our GM and VP Engineering on direction.

What We Offer – Belgium

• Health Insurancethrough Alan (100% hospitalisation cover, 80% ambulatory and dental)
• Mobility Budgetfor eco-transport, housing, or car allowance (flexible 3-pillar system)
• Group Insurance Planwith6–12% employer pension contributionbased on seniority
• Meal Vouchers(€8/day) andEco Vouchersfor sustainable purchases
• A hub-based hybrid model that blends flexibility with purpose — connecting teams through collaboration, learning, and a vibrant social culture.

Equal Opportunities & GDPR Notice

CluePoints is an equal opportunities employer. We value and respect diversity in our workforce and do not tolerate discrimination based on gender, age, disability, ethnic origin, religion, sexual orientation, or any other protected ground under Belgian law.

Personal data collected as part of your application will be processed in compliance with the EU GDPR and Belgian data protection legislation.

You have the right to access, correct, or delete your personal data at any time by contacting [e-mail] .

At CluePoints, we believe that diverse teams make better decisions and drive innovation. We’re committed to building a workplace that reflects the communities we serve and where everyone can thrive.