Postdoc in Dolichol Metabolism & CDG Discovery (ERC Start)

KU Leuven; Vlaams-Brabant; On-site; EUR 52,000 - 76,000; Full time

Benefits offered by this job

Full-time contract

1-year contract with possible renewal

Travel opportunities

KU Leuven salary scale

State-of-the-art facilities

International collaboration

Job summary

KU Leuven invites applications for a full-time Postdoctoral researcher to join the Laboratory of Prof. Matthew Wilson. The project investigates missing elements in the metabolism of dolichol within glycosylation pathways and related health implications.

You will work with CRISPR/Cas9, cell culture, and LC-MS metabolomics, collaborating across international networks. The position is funded by an ERC Starting Grant and offers opportunities for independent research, supervision of students, and

Qualifications

• PhD in Biomedical Sciences, Medicine, Biochemistry, Bioengineering or a related field.
• Excellent publication record and ability to disseminate results at international conferences.
• Passion for science and ability to pursue own ideas.
• Creative, dynamic and analytical mindset.
• Excellent spoken and written English (C1).
• Prior training in molecular biology techniques and cell culture.
• Prior training and a strong track record in biochemistry, enzymology and lipid metabolism methods.

Responsibilities

• Identify missing steps in the metabolism of dolichol using diverse methodologies.
• Develop cellular models using CRISPR/Cas9 and other gene-editing techniques.
• Conduct enzymological analyses of lipid metabolism pathways.
• Perform LC-MS–based lipid or metabolomics analyses in collaboration with related KU Leuven groups.
• Work independently, contribute ideas, and present data at weekly lab meetings.

Skills

DNA manipulation

RNA manipulation

Protein manipulation

Mammalian cell culture

Bacteria culture

Independent research

Data presentation

Education

PhD in Biomedical Sciences or related field

Tools

CRISPR/Cas9

LC-MS

Lentiviral transduction

Mass spectrometry

Job description

KU Leuven invites applications for a full-time Postdoctoral researcher to join the Laboratory of Prof. Matthew Wilson. The project investigates missing elements in the metabolism of dolichol within glycosylation pathways and related health implications.

You will work with CRISPR/Cas9, cell culture, and LC-MS metabolomics, collaborating across international networks. The position is funded by an ERC Starting Grant and offers opportunities for independent research, supervision of students, and