PhD Researcher: S. aureus Persistence in Bone Infections

Université Catholique de Louvain (UCL); Belgique; On-site; EUR 20,000 - 27,000; Full time

Job summary

Université Catholique de Louvain (UCLouvain) in Brussels, Belgium, invites applications for a PhD position investigating host–pathogen interactions that promote Staphylococcus aureus persistence in chronic bone and joint infections.

The project, part of a European consortium, uses multi-omics, flow cytometry, and single‑cell analyses to identify persistence mechanisms and potential biomarkers predicting relapse.

Qualifications

• Master's degree in biology or related field.
• Experience or strong interest in microbiology and flow cytometry.
• Willingness to work in a multidisciplinary and international environment.

Responsibilities

• Characterize uptake and intracellular fate of clinical S. aureus isolates in human monocytes and macrophages.
• Investigate bacterial susceptibility to antimicrobial treatments and decipher host and bacterial responses via multi-omics.
• Develop single-cell analyses using fluorescent biosensor-expressing strains to study heterogeneity of adaptation and survival.

Skills

microbiology

mammalian cell culture

molecular biology

flow cytometry

anti-infective pharmacology

Education

Master's degree in Biological sciences

Master's degree in Pharmacological sciences

Job description

Université Catholique de Louvain (UCLouvain) in Brussels, Belgium, invites applications for a PhD position investigating host–pathogen interactions that promote Staphylococcus aureus persistence in chronic bone and joint infections.

The project, part of a European consortium, uses multi-omics, flow cytometry, and single‑cell analyses to identify persistence mechanisms and potential biomarkers predicting relapse.