Head of Lab Operations

Signatur Biosciences Ltd; Henegouwen; Presencial; EUR 120.000 - 180.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Equity (stock options)

Mobility package

Annual leave

Descripción de la vacante

Signatur Biosciences seeks a highly motivated Head of Laboratory Operations to establish and operate our Charleroi lab facility in Belgium. You will oversee R&D, manufacturing and daily lab activities, ensuring quality, safety and regulatory compliance while building a high-performing team.

As senior on-site leader you will recruit, mentor and drive process improvements, coordinating with other departments to accelerate diagnostic development.

Formación

• Bachelor's or Master's degree in biological sciences.
• 5+ years direct line management experience in a lab management role.
• Medical diagnostic, or equivalent, industry experience.
• Fluent in English and French, both written and verbally.
• Working with Biobank regulations
• Working to ISO13485
• Knowledge of IVD/manufacturing product transfer
• Molecular Biology (qPCR, nucleic acid extraction)
• Inventory management and procurement processes
• Familiarity with Python for scientific computing

Responsabilidades

• Line Management and leadership of personnel, including hiring, training, supervision, and professional development creating of a high performing team culture
• Managing the labs daily activities, including R&D, manufacturing and daily maintenance, ensuring the accuracy and reliability of lab results and a right-first-time mindset
• Responsible for the establish and maintenance of a BioBank for human samples in compliance with national and international requirements
• Responsible for ensuring a safe work environment in compliance with all relevant Health and Safety requirements
• Ensure laboratory instrumentation qualifications are established and maintained and the laboratory complies with all relevant regulatory requirements
• Establish and maintain laboratory procedures and work instructions within the Quality Management System (QMS) framework
• Coordinates the use of lab resources, such as equipment, and act as a key contact for suppliers to ensure an efficient laboratory operation
• Generates metrics and key performance indicators (KPIs) to monitor lab performance to ensure continuous improvement.
• Manage the labs budget, including procurement and cost control
• Coordinates with other departments and external partners to support lab activities

Conocimientos

Bachelor's or Master’s degree in bio

>5 years direct line management in a-l

Medical diagnostics industry

Fluent in English & French

Biobank regulations

ISO13485

IVD/manufacturing product transfer

Molecular biology (qPCR)

Inventory management

Python

Fluent in Flemish

Educación

Bachelor's or Master's degree in biological sciences

Herramientas

Python

Descripción del empleo

Today, precision medicine coupled with advanced diagnostics is taking over. However, those innovations in medicine come with an ever-increasing price tag driven by more expensive and complicated solutions making them less accessible unless we do something about it.

Signatur Biosciences was established with the mission of making cutting-edge diagnostic tools accessible to more patients around the world. As a startup we have developed a technology to profile complex molecular signatures in a single reaction using qPCR machines already in place in every biomedical lab around the world. Signatur Biosciences is a startup currently based in New Heaven, Connecticut, and London, UK, and in the next exciting phase of expansion is establishing laboratory facilities in Charleroi (BioPark in Gosselies), Belgium.

We're worried about accessibility in precision diagnostics and are building a team of individuals who share our passion for solving this problem through close collaboration and a sense of urgency. We're building a different kind of company, where employees think like owners, act with authority, and collaborate closely with one another.

We are seeking a highly motivated and driven Head of Laboratory Operations to join our team. In this role, under the direction of the Head of Development, you will be responsible for the establishment, maintenance and operations of the laboratory facility. As a central figure in our growing organization, you will be expected to work collaboratively across the company ensuring a laboratory facility that enables the development, verification, validation and manufacture of our diagnostics assays. If you are a self-starter with a passion for novel diagnostics development, we'd love to speak with you!

About the role:

The Head of Laboratory Operations is a critical role for Signatur Biosciences as we establish our laboratory facility and expand our team. As part of a medical diagnostic start-up, the Head of Laboratory Operations will oversee all laboratory activities in both an R&D and operations setting. The Head of Laboratory Operations will have responsibility for the establishment, maintenance and operations of the laboratory facility ensuring both the quality and quantity of output in compliance with relevant industry standards. As the senior on-site leader, the Head of Laboratory Operations will have a key role in the recruitment, management and motivation of the team, leading by example and creating a high performing team environment.

Skills, Experience & Attributes

• Bachelor s or Master s degree in biological sciences
• >5 years direct line management experience in a lab management (or equivalent) role
• Medical diagnostic, or equivalent, industry experience
• Fluent in English and French, both written and verbally.
• Working with Biobank regulations
• Working to ISO13485
• Knowledge of IVD/manufacturing product transfer
• Molecular Biology (qPCR, nucleic acid extraction)
• Inventory management and procurement processes
• Familiarity with scientific computing languages (i.e. Python)
• Fluent in Flemish, both written and verbally

Main Responsibilities:

People and Functional Development

• Line Management and leadership of personnel, including hiring, training, supervision, and professional development creating of a high performing team culture
• Managing the labs daily activities, including R&D, manufacturing and daily maintenance, ensuring the accuracy and reliability of lab results and a right-first-time mindset
• Responsible for the establish and maintenance of a BioBank for human samples in compliance with national and international requirements
• Responsible for ensuring a safe work environment in compliance with all relevant Health and Safety requirements
• Ensure laboratory instrumentation qualifications are established and maintained and the laboratory complies with all relevant regulatory requirements
• Establish and maintain laboratory procedures and work instructions within the Quality Management System (QMS) framework
• Coordinates the use of lab resources, such as equipment, and act as a key contact for suppliers to ensure an efficient laboratory operation
• Generates metrics and key performance indicators (KPIs) to monitor lab performance to ensure continuous improvement.
• Manage the labs budget, including procurement and cost control
• Coordinates with other departments and external partners to support lab activities
• Act as the point of contact for the landlord, forming close and collaborative working arrangement and ensuring optimal usage of share facilities
• Responsible for the evolution of lab space to meet changing company needs, working with internal and external stakeholders to ensure

Project and Product Delivery

• Key contributor to writing and reviewing grant proposals, forming contacts within the local bioscience ecosystem
• Directly contribute to tasks, facilitating and assisting with project delivery
• Clearly communicate business priorities to team members and remove obstacles to enable focus on priority tasks
• Support and/or lead troubleshooting activities using root cause analysis tools
• May act as an independent reviewer at project design review meetings
• Develops personal skills to think creatively and solve problems uniquely
• Leverages the diverse perspectives and skills of the group to create innovative solutions

Sense of Urgency

• Recognizes what needs immediate attention, acting without delays
• Ensures team members work together efficiently to meet collective goals

Focus

• Single minded in the pursuit of tasks without distractions, setting priorities and managing time effectively
• Fosters an environment where team members can concentrate on their roles and collaborate effectively

Change Management

• Demonstrates personal adaptability and resilience
• Constructively handles changes in daily routine or adapting to new technologies/approaches
• Leads by example, facilitating change through proactively engaging team members to discuss changes, provides training and addressed concerns collectively.

Competitive base salary + Equity (stock options)

Mobility package

Annual leave

Others

As we continue to grow, our benefits package will evolve. The benefits outlined above are accurate as of the job posting date, but may differ at time of hire.

Further information

Signatur Biosciences is an equal-opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.

Legal authorization to work in the UK is required. In compliance with UK law, all persons hired will be required to verify identity and eligibility to work in the UK and to complete the required employment eligibility verification form upon hire.