Associate Director, Statistical Modeling and Simulation

argenx; Gent; Hybride; EUR 100 000 - 138 000; Plein temps

Avantages offerts par ce poste

Incentives program

Résumé du poste

argenx is seeking a senior statistician to lead the development and implementation of innovative study designs in clinical trials, including adaptive designs and Bayesian approaches. You will pilot AI/ML solutions for disease modeling and collaborate across Quantitative Sciences to translate evidence into data-driven decisions.

Applicants should hold a PhD in Statistics or Biostatistics with 6+ years in pharma/biotech, and be located in Belgium or the US (EST).

Qualifications

• PhD in Statistics, Biostatistics, or related field with 6+ years of pharma/biotech clinical development experience (or equivalent).
• Strong track record of proposing and implementing innovative trial designs.
• Candidates must be located in Belgium or US (EST time zone) to be considered for this role.

Responsabilités

• Lead the development and implementation of innovative study design and analysis methods in clinical trials, such as adaptive designs, external/hybrid/synthetic control, model-informed drug development, and Bayesian approaches.
• Pilot and integrate fit-for-purpose AI/ML solutions for disease modeling and precision-medicine applications, building the internal capability and external partnerships to leverage emerging technology and diverse data sources with statistical and scientific rigor.
• Partner with cross-functional teams to integrate internal and external evidence in a quantitative framework and translate it into transparent, data-driven decision recommendations.
• Provide statistical consultation on study design and analysis to address challenges in clinical projects.
• Contribute statistical expertise to regulatory interactions on novel and complex designs, including preparing briefing materials and engaging with health authorities.
• Strengthen organizational capability in innovative drug development by mentoring junior statisticians and leading trainings and seminars on advanced methodologies and their practical implementation.
• Contribute to and influence the external scientific community on behalf of argenx through publications, presentations, and industry and academic collaborations.

Connaissances

Pharma statistics

Data science

R

Python

Cloud computing

Formation

PhD in Statistics/Biostatistics

Outils

R

Python

Git

Description du poste

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.

We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients.

PURPOSE OF THE FUNCTION

The Statistical Modeling and Innovative Solutions team partners with colleagues across Quantitative Sciences and other cross-functional teams to develop and apply innovative approaches to optimize study designs and clinical development plans, strengthen data‑driven decisions, and support evidence and insights generation across the argenx portfolio.

REPORTING LINE

• Head of Statistical Modeling & Innovative Solutions

Roles And Responsibilities

• Lead the development and implementation of innovative study design and analysis methods in clinical trials, such as adaptive designs, external/hybrid/synthetic control, model-informed drug development, and Bayesian approaches.
• Pilot and integrate fit-for-purpose AI/ML solutions for disease modeling and precision-medicine applications, building the internal capability and external partnerships to leverage emerging technology and diverse data sources with statistical and scientific rigor.
• Partner with cross-functional teams to integrate internal and external evidence in a quantitative framework and translate it into transparent, data-driven decision recommendations.
• Provide statistical consultation on study design and analysis to address challenges in clinical projects.
• Contribute statistical expertise to regulatory interactions on novel and complex designs, including preparing briefing materials and engaging with health authorities.
• Strengthen organizational capability in innovative drug development by mentoring junior statisticians and leading trainings and seminars on advanced methodologies and their practical implementation.
• Contribute to and influence the external scientific community on behalf of argenx through publications, presentations, and industry and academic collaborations.

Skills And Competencies

• Demonstrated expertise in advanced methodologies in pharmaceutical statistics and data science
• Excellent modeling and simulation capabilities, with advanced proficiency in statistical programming languages such as R and Python, and familiarity with cloud computing and version control systems.
• Strong communication and influencing skills to enable effective interdisciplinary collaboration.

Education, Experience And Qualifications

• PhD in Statistics, Biostatistics, or related field with 6+ years of relevant pharma/biotech clinical development experience (or equivalent).
• Strong track record of proposing and implementing innovative trial designs.
• Candidates must be located in Belgium or US (EST time zone) to be considered for this role.

The annual base salary hiring range for this position is €100,000.00 - €137,500.00 EUR

This job is eligible to participate in our short-term and long-term incentives program.

The hiring range displayed above is the range of possible base pay compensation that argenx believes in good faith it will pay for this role at the time of this posting. The hiring range is based on the job grade for this position. Individual compensation paid within this range depends on a variety of factors, including, but not limited to, internal equity, prior education and experience, job‑related knowledge and demonstrated skills. argenx may pay more or less than the posted range and this range may be modified in the future.

At argenx, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer.