Associate Director, Statistical Modeling and Simulation

argenx SE; Oost-Vlaanderen; Sur place; EUR 100 000 - 138 000; Plein temps

Avantages offerts par ce poste

Incentives program

Résumé du poste

argenX is seeking a lead in Statistical Modeling and Innovative Solutions to advance study design and analyses in clinical development, including adaptive designs, external/hybrid controls, model-informed drug development, and Bayesian methods. You will pilot AI/ML approaches with rigor.

PhD in Statistics or Biostatistics with 6+ years in pharma/biotech, and location in Belgium or US (EST). The role offers €100,000–€137,500 base and participation in incentives, supporting a global immunology

Qualifications

• PhD in Statistics, Biostatistics, or related field with 6+ years pharma/biotech clinical development experience.
• Strong track record of proposing and implementing innovative trial designs.
• Candidates must be located in Belgium or US (EST time zone) to be considered for this role.

Responsabilités

• Lead the development and implementation of innovative study design and analysis methods in clinical trials, such as adaptive designs, external/hybrid/synthetic control, model-informed drug development, and Bayesian approaches.
• Pilot and integrate fit-for-purpose AI/ML solutions for disease modeling and precision-medicine applications, building internal capability and external partnerships with statistical rigor.
• Partner with cross-functional teams to integrate internal and external evidence in a quantitative framework and translate it into data-driven decision recommendations.
• Provide statistical consultation on study design and analysis to address challenges in clinical projects.
• Contribute statistical expertise to regulatory interactions on novel and complex designs, including preparing briefing materials and engaging with health authorities.
• Strengthen organizational capability in innovative drug development by mentoring junior statisticians and leading trainings and seminars on advanced methodologies and their practical implementation.

Connaissances

Advanced statistics

R/Python

Communication skills

Formation

PhD in Statistics/Biostatistics or related field

Outils

R

Python

Cloud computing

Git

Description du poste

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases. We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients.

Purpose of the Function

The Statistical Modeling and Innovative Solutions team partners with colleagues across Quantitative Sciences and other cross-functional teams to develop and apply innovative approaches to optimize study designs and clinical development plans, strengthen data‑driven decisions, and support evidence and insights generation across the argenx portfolio.

Reporting Line

Head of Statistical Modeling & Innovative Solutions

Roles and Responsibilities

• Lead the development and implementation of innovative study design and analysis methods in clinical trials, such as adaptive designs, external/hybrid/synthetic control, model-informed drug development, and Bayesian approaches.
• Pilot and integrate fit-for-purpose AI/ML solutions for disease modeling and precision-medicine applications, building the internal capability and external partnerships to leverage emerging technology and diverse data sources with statistical and scientific rigor.
• Partner with cross-functional teams to integrate internal and external evidence in a quantitative framework and translate it into transparent, data-driven decision recommendations.
• Provide statistical consultation on study design and analysis to address challenges in clinical projects.
• Contribute statistical expertise to regulatory interactions on novel and complex designs, including preparing briefing materials and engaging with health authorities.
• Strengthen organizational capability in innovative drug development by mentoring junior statisticians and leading trainings and seminars on advanced methodologies and their practical implementation.
• Contribute to and influence the external scientific community on behalf of argenx through publications, presentations, and industry and academic collaborations.

Skills and Competencies

• Demonstrated expertise in advanced methodologies in pharmaceutical statistics and data science
• Excellent modeling and simulation capabilities, with advanced proficiency in statistical programming languages such as R and Python, and familiarity with cloud computing and version control systems.
• Strong communication and influencing skills to enable effective interdisciplinary collaboration.

Education, Experience and Qualifications

PhD in Statistics, Biostatistics, or related field with 6+ years of relevant pharma/biotech clinical development experience (or equivalent). Strong track record of proposing and implementing innovative trial designs. Candidates must be located in Belgium or US (EST time zone) to be considered for this role.

Salary

The annual base salary hiring range for this position is €100,000.00 - €137,500.00 EUR This job is eligible to participate in our short-term and long-term incentives program. The hiring range displayed above is the range of possible base pay compensation that argenX believes in good faith it will pay for this role at the time of this posting. The hiring range is based on the job grade for this position. Individual compensation paid within this range depends on a variety of factors, including, but not limited to, internal equity, prior education and experience, job‑related knowledge and demonstrated skills. argenX may pay more or less than the posted range and this range may be modified in the future.

Equal Opportunity

At argenX, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenX is proud to be an equal opportunity employer.

About the Company

argenX is a global immunology company dedicated to improving the lives of people suffering from severe autoimmune diseases. Through our rich pipeline of first-in-class therapies, led by VYVGART®, we are accelerating progress toward our bold 2030 vision: to reach 50,000 patients and transform the landscape of autoimmune treatment. Our innovation mission combines with meaningful work and endless opportunities for growth to create once-in-a-career experiences. There's more to discover at argenX, where our passion inspires bold possibility.

Locations

argonauts work in locations around the globe including Belgium, Boston, Japan and Amsterdam.