Molecular Biologist, Genome Engineering for Antibody Discovery

One Nucleus

Town of Cambridge

Sur place

AUD 86 000 - 95 000

Plein temps

Il y a 10 jours

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Avantages offerts par ce poste

25 annual leave days
Education stipend
Equity compensation
Private Medical Insurance
Pension contribution matching

Résumé du poste

Alloy Therapeutics is seeking a Scientist I – Molecular Biology to join the GEO team at their Cambridge site. The role focuses on designing and constructing large-scale synthetic gene loci for next-generation discovery platforms, using advanced genome engineering to enable diverse therapeutic antibody discovery, including bispecifics and VHHs.

The position blends thoughtful genetic design with hands-on wet-lab work.

Qualifications

  • PhD in Developmental Biology, Functional Genetics, Molecular Biology, Immunology, Cell Biology or related field, or equivalent experience.
  • Immunology knowledge and ability to perform immunophenotypic analysis with multicolor flow cytometry.
  • Familiarity with genetic engineering and transgenic models; design of targeting and screening strategies.

Responsabilités

  • Design and construct complex gene loci to support antibody discovery platforms.
  • Perform hands-on genome engineering and model development to support generation of therapeutics.
  • Ensure data quality through rigorous analysis and meticulous documentation.

Connaissances

CRISPR/Cas9
Immunology
Molecular biology
Flow cytometry
Genetic engineering
Animal models
NGS
V(D)J recombination

Formation

PhD in Developmental Biology or related

Outils

Geneious Prime
Benchling
FlowJo

Description du poste

Alloy Therapeutics is seeking a Scientist I – Molecular Biology to join the GEO team at their Cambridge site. The role focuses on designing and constructing large-scale synthetic gene loci for next-generation discovery platforms, using advanced genome engineering to enable diverse therapeutic antibody discovery, including bispecifics and VHHs.

The position blends thoughtful genetic design with hands-on wet-lab work.

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