Senior Research Chemist

Placements24; Centurion; Hybrid; ZAR 900.000 - 1.500.000; Vollzeit

Zusammenfassung

Placements24 in Centurion, Gauteng, seeks a Senior Research Chemist to advance our drug discovery program through synthetic organic chemistry, design, synthesis, and characterization of novel molecules.

The ideal candidate holds a Ph.D. in Organic Chemistry with at least 5 years of post-PhD experience, a strong publication record, and proven ability to translate concepts into scalable processes.

Qualifikationen

• Ph.D. in Organic Chemistry or closely related field is required.
• Minimum of 5 years of post-doctoral or industry experience in synthetic organic chemistry.
• Expertise in modern synthetic organic chemistry methodologies including asymmetric synthesis and catalysis.
• Extensive experience with NMR, MS, HPLC, IR for compound characterization.
• Strong problem-solving skills and capacity for independent research.
• Excellent written and verbal communication skills.
• Experience with process chemistry and scale-up is advantageous.
• Ability to work in a collaborative, cross-functional team and publish findings.

Aufgaben

• Design and execute multi-step synthetic routes for novel organic compounds.
• Characterize synthesized compounds using NMR, Mass Spectrometry, HPLC, and IR spectroscopy.
• Optimize reaction conditions and develop robust synthetic procedures suitable for scale-up.
• Investigate and troubleshoot synthetic challenges to achieve desired outcomes efficiently.
• Collaborate with medicinal chemists, biologists, and analytical chemists to advance drug discovery programs.
• Maintain comprehensive and accurate laboratory notebooks and research reports.
• Stay updated on the latest advancements in synthetic organic chemistry and relevant literature.
• Present research findings and progress updates to project teams and management.
• Ensure compliance with all laboratory safety regulations and ethical standards.
• Contribute to intellectual property generation through patentable inventions.

Kenntnisse

Analytical techniques

Asymmetric synthesis

Catalysis

Independent research

Written and verbal communication

Ausbildung

Ph.D. in Organic Chemistry

Tools

ChemDraw

Jobbeschreibung

About the Role

Our client, a globally recognized leader in the pharmaceutical and chemical industry, is seeking a highly accomplished Senior Research Chemist to join their innovative R&D department in Centurion, Gauteng . This challenging role focuses on the design, synthesis, and characterization of novel organic molecules with potential therapeutic applications. You will play a critical part in advancing our drug discovery pipeline, contributing expertise in synthetic organic chemistry and process development. The ideal candidate is a meticulous, creative, and results-oriented chemist with a passion for pushing the boundaries of chemical science. This is an excellent opportunity to contribute to impactful research and development within a supportive and intellectually stimulating environment, driving forward the creation of next-generation medicines. Your contributions will directly influence the progression of vital research projects.

Key Responsibilities

• Design and execute multi-step synthetic routes for novel organic compounds.
• Perform detailed characterization of synthesized compounds using techniques such as NMR, Mass Spectrometry, HPLC, and IR spectroscopy.
• Optimize reaction conditions and develop robust synthetic procedures suitable for scale-up.
• Investigate and troubleshoot synthetic challenges to achieve desired outcomes efficiently.
• Collaborate with medicinal chemists, biologists, and analytical chemists to advance drug discovery programs.
• Maintain comprehensive and accurate laboratory notebooks and research reports.
• Stay updated on the latest advancements in synthetic organic chemistry and relevant literature.
• Present research findings and progress updates to project teams and management.
• Ensure compliance with all laboratory safety regulations and ethical standards.
• Contribute to intellectual property generation through patentable inventions.

Requirements

• Ph.D. in Organic Chemistry or a closely related field.
• A minimum of 5 years of post-doctoral or industry experience in synthetic organic chemistry.
• Proven expertise in modern synthetic organic chemistry methodologies, including asymmetric synthesis and catalysis.
• Extensive experience with a broad range of analytical techniques for compound characterization.
• Demonstrated ability to design and execute complex synthetic sequences.
• Strong problem-solving skills and a capacity for independent research.
• Excellent written and verbal communication skills.
• Experience with process chemistry and scale-up considerations is advantageous.
• Ability to work effectively in a collaborative, cross-functional team environment.
• Proficiency in chemical drawing software and literature search databases.
• A track record of publications in peer-reviewed journals is expected.

Benefits

Our client provides a competitive compensation package, including a performance-based bonus structure and comprehensive benefits such as medical aid, provident fund, and life insurance. Opportunities for continuous learning and professional development are strongly supported through internal training programs, external workshops, and conference attendance. The work environment in Centurion, Gauteng is dynamic and collegial, fostering innovation and scientific rigor. Employees are encouraged to contribute ideas and take ownership of their projects. Potential for career growth within a global organization is significant, with pathways to leadership roles. We are committed to fostering an inclusive and diverse workplace.