Senior Process Chemist - API Development & Scale-Up

Placements24; Randburg; Vor Ort; ZAR 900.000 - 1.200.000; Vollzeit

Benefits dieser Stelle

Medical insurance

Life insurance

Retirement fund

Career progression opportunities

Zusammenfassung

Placements24 seeks an experienced Senior Process Chemist for our pharmaceutical client in Randburg to lead API process development from lab scale to pilot and full production. The role emphasizes robust synthetic routes, safety, and cost-efficiency within a collaborative R&D team.

The candidate will design experiments, optimize reaction conditions, and develop analytical methods while ensuring regulatory compliance and cross-functional teamwork with analytical, engineering, and manufacturing

Qualifikationen

• Ph.D. or Master’s in Organic Chemistry, Chemical Engineering, or related field.
• Minimum of 5 years of industrial experience in process chemistry for pharm APIs.
• Proven expertise in synthetic route design, optimization and scale-up.
• Knowledge of cGMP and regulatory requirements.

Aufgaben

• Develop and optimize synthetic routes for APIs and intermediates with focus on yield, purity, safety and cost;
• Scale up laboratory processes to pilot plant and manufacturing scales;
• Conduct process hazard assessments and implement safety measures;
• Develop robust analytical methods for in-process controls and release;
• Mentor junior chemists and collaborate with regulatory affairs.

Kenntnisse

Synthetic route design

Process optimization

Scale-up

Hazard analysis

cGMP knowledge

Analytical collaboration

Ausbildung

Ph.D. or Master’s in Organic Chemistry or Chemical Engineering

Tools

HPLC

GC

MS

NMR

Jobbeschreibung

Placements24 seeks an experienced Senior Process Chemist for our pharmaceutical client in Randburg to lead API process development from lab scale to pilot and full production. The role emphasizes robust synthetic routes, safety, and cost-efficiency within a collaborative R&D team.

The candidate will design experiments, optimize reaction conditions, and develop analytical methods while ensuring regulatory compliance and cross-functional teamwork with analytical, engineering, and manufacturing