Senior/Principal Statistical Programmer – Remote (SAS + R)

London Early Years Foundation (Leyf); East London; Remote; ZAR 1,985,000 - 2,978,000; Full time

Job summary

Cytel Inc. is seeking a Senior/Principal Statistical Programmer with remote work flexibility to lead programming for one or more pharma programs. The role emphasizes SDTM/ADaM, Define.xml, and delivering high‑quality datasets, listings and graphs.

You will oversee CROs, ensure timelines, and contribute to regulatory submissions in a highly capable biostatistics team. Ideal candidates have extensive SAS experience, CDISC standards mastery, and the ability to work independently while communicating

Qualifications

• Bachelor's degree in CS, data science, math or stats.
• 7+ years as Statistical Programmer in biotech/pharma.
• Strong SAS programming skills and CDSIC standards knowledge.
• Experience supporting regulatory submissions.
• Able to work with CROs and cross‑functional teams.
• Excellent written and verbal communication.
• Independent worker with problem solving ability.

Responsibilities

• Generate SDTM, ADaM specifications and define.xml files for studies.
• Develop SAS programs for datasets, listings, tables and graphs.
• Deliver high‑quality programming results for clinical development programs.
• Oversee CRO's statistical programming deliverables for timelines and quality.
• Support CSR, regulatory submissions, publications and DSURs.
• Follow FDA/ICH, GCP and electronic submission guidelines.
• Contribute to standards for programming tools, outputs and macros.
• Develop CRFs, edit checks and data validation plans.
• Provide input on data transfer specifications for external vendors.
• Collaborate with internal/external partners to meet project goals.
• Contribute to SOPs and Work Instructions related to programming.

Skills

SAS programming

Leadership

Communication

CDISC SDTM/ADaM

Regulatory submissions experience

Education

Bachelor's degree in Computer Science / Data Science / Mathematics / Statistics

Tools

R

Python

Java

Shiny

Unix/Linux

Git

Job description

Cytel Inc. is seeking a Senior/Principal Statistical Programmer with remote work flexibility to lead programming for one or more pharma programs. The role emphasizes SDTM/ADaM, Define.xml, and delivering high‑quality datasets, listings and graphs.

You will oversee CROs, ensure timelines, and contribute to regulatory submissions in a highly capable biostatistics team. Ideal candidates have extensive SAS experience, CDISC standards mastery, and the ability to work independently while communicating