Senior Pharmacologist - Preclinical Research

Placements24; LegKraal Gate; On-site; ZAR 1,200,000 - 1,500,000; Full time

Job summary

Placements24 is seeking a highly experienced Senior Pharmacologist to join its preclinical research team in Mahikeng. The role centers on designing and conducting in vivo studies to evaluate the efficacy and safety of novel therapeutic compounds, and leading research projects within a state-of-the-art facility.

You will interpret complex pharmacological data, contribute to drug discovery, ensure GLP-compliant work, and collaborate with medicinal chemists, toxicologists, and project managers to

Qualifications

• PhD in Pharmacology, Toxicology, or related life science discipline.
• Minimum of 6 years in preclinical drug discovery with strong in vivo pharmacology focus.
• Proven expertise in experimental design, data analysis, and interpretation of pharmacological data.

Responsibilities

• Design, execute, and interpret complex in vivo pharmacology studies to assess drug efficacy, pharmacodynamics, and toxicology.
• Develop and validate preclinical models relevant to specific disease areas.
• Analyze and report on study results, including data interpretation and statistical analysis.
• Collaborate with cross-functional teams to advance drug candidates.
• Ensure studies are conducted in compliance with GLP and regulatory requirements.
• Contribute to regulatory submissions and scientific publications.

Skills

In vivo pharmacology

Experimental design

Data analysis

Regulatory knowledge GLP

Leadership

Education

PhD in Pharmacology/Toxicology

Job description

About the Role

Our client is seeking a highly experienced Senior Pharmacologist to join their preclinical research division in Mahikeng . This critical role focuses on designing and conducting in vivo studies to evaluate the efficacy and safety of novel therapeutic compounds. You will be responsible for leading research projects, interpreting complex pharmacological data, and contributing to the drug discovery and development pipeline. The ideal candidate will possess a deep understanding of pharmacology, experimental design, and regulatory requirements for preclinical studies, working within a state-of-the-art research facility committed to advancing new medicines.

Key Responsibilities

• Design, execute, and interpret complex in vivo pharmacology studies to assess drug efficacy, pharmacodynamics, and toxicology.
• Develop and validate preclinical models relevant to specific disease areas.
• Analyze and report on study results, including data interpretation, statistical analysis, and presentation of findings.
• Collaborate with cross-functional teams, including medicinal chemists, toxicologists, and project managers, to advance drug candidates.
• Ensure all studies are conducted in compliance with relevant ethical guidelines and regulatory requirements (e.g., GLP).
• Contribute to the preparation of regulatory submissions and scientific publications.

Requirements

• PhD in Pharmacology, Toxicology, or a closely related life science discipline.
• Minimum of 6 years of experience in preclinical drug discovery and development, with a strong focus on in vivo pharmacology.
• Proven expertise in experimental design, data analysis, and interpretation of pharmacological data.
• Hands-on experience with a variety of animal models and dosing routes.
• Knowledge of Good Laboratory Practice (GLP) regulations and their application in preclinical research.
• Excellent communication, leadership, and project management skills.

Benefits

• Competitive salary and comprehensive benefits package, including bonuses.
• Health, dental, and vision insurance coverage.
• Retirement savings plan with employer matching.
• Generous paid time off and professional development opportunities.
• A challenging and rewarding research career at the forefront of drug discovery in Mahikeng .