Senior Pharma Process Development Scientist - Hybrid

Placements24; Upington; Hybrid; ZAR 1,200,000 - 2,100,000; Full time

Benefits offered by this job

Medical insurance

Retirement contributions

Paid time off

Professional development opportunities

Job summary

Placements24 is seeking a Senior Pharmaceutical Process Development Scientist for our client in Upington, Northern Cape. The role focuses on optimizing and scaling manufacturing processes for APIs and drug products, ensuring GMP compliance and robust tech transfer to commercial operations.

The position offers a hybrid work arrangement with on-site lab and pilot plant activities alongside remote analysis and documentation, collaborating across formulation, analytical development, and

Qualifications

• Ph.D. in Chemical Engineering, Pharmaceutical Sciences, or related field.
• Minimum of 5 years of experience in pharmaceutical process development and scale-up.
• Proven experience optimizing chemical or biological manufacturing processes.
• Strong understanding of GMP, process validation, and regulatory requirements.

Responsibilities

• Develop, optimize, and scale-up manufacturing processes for Active Pharmaceutical Ingredients (APIs) and drug products.
• Design and execute experiments to understand process parameters and critical quality attributes.
• Conduct process hazard analyses and ensure the safety of all operations.
• Develop process validation strategies and protocols.
• Troubleshoot manufacturing issues and implement corrective and preventive actions (CAPAs).
• Collaborate with analytical development to establish appropriate in‑process controls and specifications.
• Author process development reports and contribute to regulatory filings (e.g., IND, NDA).
• Evaluate and implement new process technologies and equipment.
• Ensure compliance with GMP, safety, and environmental regulations.
• Mentor junior scientists and engineers within the process development team.

Skills

Chemical engineering

Process chemistry

Analytical skills

Regulatory understanding

Education

Ph.D. in Chemical Engineering, Pharmaceutical Sciences, or related field

Tools

Process modeling software

Simulation software

Job description

Placements24 is seeking a Senior Pharmaceutical Process Development Scientist for our client in Upington, Northern Cape. The role focuses on optimizing and scaling manufacturing processes for APIs and drug products, ensuring GMP compliance and robust tech transfer to commercial operations.

The position offers a hybrid work arrangement with on-site lab and pilot plant activities alongside remote analysis and documentation, collaborating across formulation, analytical development, and