Senior Formulation Scientist (Pharmaceuticals)

Placements24; Rustenburg; Sur place; ZAR 900 000 - 1 200 000; Plein temps

Avantages offerts par ce poste

Competitive salary

Bonus structure

Medical aid

Life insurance

Pension fund

Training programs

Conference participation

Résumé du poste

Placements24 in Rustenburg, North West, ZA is seeking a Senior Formulation Scientist to lead the design, development and optimization of drug delivery systems and finished dosage forms in its R&D division.

This role requires expertise in formulation development, excipient selection and manufacturing scale-up, with responsibility for analytical method development and regulatory compliance in a collaborative, multidisciplinary team.

Qualifications

• Ph.D. or Master’s in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or related field.
• 5–7 years hands-on experience in pharmaceutical formulation development.
• Proven track record in developing various dosage forms, including oral solids.
• In-depth knowledge of excipient functionalities, compatibility and selection.
• Experience with HPLC, DSC, TGA, XRPD and dissolution testing.
• GMP principles in formulation development and manufacturing.
• Strong project management and problem solving skills.
• Excellent written and verbal communication abilities.

Responsabilités

• Design and develop stable, manufacturable pharmaceutical formulations.
• Conduct pre-formulation studies and API/excipient characterization.
• Optimize formulations and processes for viability and regulatory compliance.
• Perform laboratory-scale formulation development and characterization.
• Develop and validate analytical methods for drug products.
• Troubleshoot formulation and manufacturing process issues.
• Manage formulation development projects and milestones.
• Collaborate with analytical, process development and regulatory teams.
• Stay updated on advancements in formulation science and drug delivery.
• Prepare technical reports and regulatory documentation.

Connaissances

Pharmaceutical formulation

excipient selection

HPLC

Formation

PhD in Pharmaceutical Sciences

Master's in related field

Outils

DSC

TGA

XRPD

Dissolution testing

Description du poste

Our client, a forward-thinking pharmaceutical company, is actively seeking a highly skilled Senior Formulation Scientist to join their Research and Development division in Rustenburg, North West, ZA . This pivotal role focuses on the design, development, and optimization of innovative drug delivery systems and finished dosage forms. The ideal candidate will possess extensive expertise in pharmaceutical formulation development, excipient selection, and manufacturing process scale-up. You will play a key role in advancing the company's product pipeline, contributing significantly to the creation of effective and patient-centric pharmaceutical products. This position offers a unique opportunity to work in a state-of-the-art facility in Rustenburg, North West, ZA .

Key Responsibilities

• Design and develop stable, effective, and manufacturable pharmaceutical formulations (e.g., solid dosage forms, liquids, semi-solids).
• Conduct pre-formulation studies, including characterization of active pharmaceutical ingredients (APIs) and excipients.
• Optimize formulations and manufacturing processes for commercial viability and regulatory compliance.
• Perform laboratory-scale formulation development and characterization using various analytical techniques.
• Develop and validate analytical methods for the characterization of drug products.
• Troubleshoot formulation and manufacturing process issues.
• Manage formulation development projects, ensuring timely completion of milestones.
• Collaborate with analytical development, process development, and regulatory affairs teams.
• Stay updated on the latest advancements in pharmaceutical formulation science and drug delivery technologies.
• Prepare technical reports, documentation for regulatory submissions, and present findings.

Requirements

• Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related discipline.
• Minimum of 5-7 years of hands-on experience in pharmaceutical formulation development.
• Proven track record in developing various dosage forms, including oral solid dosage forms.
• In-depth knowledge of excipient functionalities, compatibility, and selection.
• Experience with analytical techniques such as HPLC, DSC, TGA, XRPD, and dissolution testing.
• Understanding of GMP principles and their application in formulation development and manufacturing.
• Strong project management and problem-solving skills.
• Excellent written and verbal communication abilities.
• Ability to work independently and collaboratively within a multidisciplinary team.
• Must be able to work full-time on-site in Rustenburg, North West, ZA .

Benefits

• Our client offers a highly competitive salary, attractive bonus structures, and a comprehensive benefits package including medical aid, life insurance, and a pension fund.
• Opportunities for continuous learning and professional development are provided through training programs and conference participation.
• The company fosters a stimulating and innovative work environment, promoting a healthy work-life balance.
• You will work with cutting-edge technology and contribute to developing life-changing medicines from our facility in Rustenburg, North West, ZA .