Senior Formulation Scientist – Oral Dosage Forms (Soweto)

Placements24; Soweto; On-site; ZAR 900,000 - 1,200,000; Full time

Benefits offered by this job

Medical benefits

Retirement benefits

Career development opportunities

Job summary

Placements24 is seeking a Formulation Scientist for a leading pharmaceutical manufacturer in Soweto, Gauteng. You will join the Product Development team to develop innovative and generic oral solid dosage forms (tablets, capsules) and manage formulation design, pre-formulation studies, and scale-up.

Role focuses on developing high-quality medicines, collaborating with QA/QC and analytical teams, and ensuring regulatory compliance.

Qualifications

• Master's or Ph.D. degree in Pharmaceutical Sciences or related discipline.
• 4–6 years hands-on experience in formulation development of oral solid dosage forms.
• In-depth knowledge of dosage form design and manufacturing for tablets/capsules.
• Experience with pre-formulation studies and excipient selection.
• Proficiency with analytical method development/validation for oral solids.
• Knowledge of cGMP and regulatory submission requirements.
• Strong problem-solving, analytical, and organizational skills.
• Excellent communication and teamwork abilities.
• Experience in Gauteng/Soweto advantageous.

Responsibilities

• Design and develop robust formulations for tablets and capsules.
• Conduct pre-formulation studies and assess API/excipient compatibility.
• Develop and optimize manufacturing processes (granulation, compression, coating, encapsulation).
• Run laboratory-scale experiments and pilot plant trials to evaluate formulation performance.
• Scale-up formulations from laboratory to pilot and commercial manufacturing scales, ensuring reproducibility.
• Develop and validate analytical methods for assessing drug product quality (dissolution, content uniformity, hardness).
• Collaborate with analytical, process, and QA/QC teams to ensure seamless product development and technology transfer.
• Prepare technical reports, formulation development summaries, and documentation for regulatory submissions.
• Troubleshoot formulation and process-related issues encountered during development.
• Stay informed about new technologies, excipients, and regulatory trends in oral solid dosage form development.
• Ensure all activities comply with cGMP and relevant regulatory guidelines.

Skills

Formulation development

Oral solid dosage forms

Analytical method development

Pre-formulation studies

Problem-solving

Education

Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or related discipline

PhD in Pharmaceutical Sciences (preferred)

Job description

Placements24 is seeking a Formulation Scientist for a leading pharmaceutical manufacturer in Soweto, Gauteng. You will join the Product Development team to develop innovative and generic oral solid dosage forms (tablets, capsules) and manage formulation design, pre-formulation studies, and scale-up.

Role focuses on developing high-quality medicines, collaborating with QA/QC and analytical teams, and ensuring regulatory compliance.