Senior Formulation Scientist – Drug Delivery R&D (Benoni)

Placements24; Benoni; Hybrid; ZAR 900,000 - 1,200,000; Full time

Benefits offered by this job

Health insurance

Retirement plan

Professional development

Modern lab facilities

Flexible working arrangements

Competitive salary

Job summary

Placements24 is seeking a Senior Formulation Scientist in Benoni, Gauteng to lead development and optimisation of novel drug formulations for oral solids and parenteral products. You will drive pre-formulation studies, scale-up processes, and analytical method development.

The ideal candidate has 5+ years in pharmaceutical formulation development, hands-on experience with HPLC and analytical techniques, and a strong grasp of cGMP and regulatory guidelines.

Qualifications

• Master’s or Ph.D. in Pharmaceutics, Pharmaceutical Sciences, Chemical Engineering, or a related discipline.
• Minimum of 5 years of experience in pharmaceutical formulation development.
• Proven experience with a variety of dosage forms, including oral solids (tablets, capsules) and parenteral products.
• Hands-on experience with formulation development equipment and analytical techniques (e.g., HPLC, dissolution testing, particle size analysis).
• Strong understanding of drug delivery principles, pharmacokinetics, and biopharmaceutics.
• Knowledge of cGMP requirements and regulatory guidelines (e.g., FDA, EMA) related to formulation development.
• Excellent problem-solving, organisational, and communication skills.
• Ability to manage multiple projects simultaneously in a fast-paced R&D setting.

Responsibilities

• Design, develop, and optimise pharmaceutical formulations for small molecules and biologics, including oral solid dosage forms, parenteral solutions, and suspensions.
• Conduct pre-formulation studies to characterise drug substances and excipients.
• Perform stability testing on formulations and analyse results to determine shelf-life and storage conditions.
• Scale-up laboratory formulations to pilot and manufacturing scales, ensuring process robustness and reproducibility.
• Develop and validate analytical methods for the characterisation of formulated products.
• Collaborate with regulatory affairs, manufacturing, and quality assurance teams to ensure compliance with all relevant guidelines.
• Prepare technical reports, protocols, and contribute to regulatory submission documents.
• Stay updated on the latest trends and technologies in pharmaceutical formulation and drug delivery.

Skills

Analytical thinking

Project management

Team collaboration

Education

Master’s or Ph.D. in Pharmaceutics/Pharmaceutical Sciences

Tools

HPLC

Dissolution testing

Particle size analysis

Job description

Placements24 is seeking a Senior Formulation Scientist in Benoni, Gauteng to lead development and optimisation of novel drug formulations for oral solids and parenteral products. You will drive pre-formulation studies, scale-up processes, and analytical method development.

The ideal candidate has 5+ years in pharmaceutical formulation development, hands-on experience with HPLC and analytical techniques, and a strong grasp of cGMP and regulatory guidelines.