Senior Clinical Research Associate - Oncology Trials

Placements24; Polokwane; Hybrid; ZAR 482,000 - 1,033,000; Full time

Benefits offered by this job

Flexible remote work

Competitive hourly rate or project‑bas

Global team exposure

Professional development opportunities

Job summary

Placements24 seeks a Senior Clinical Research Associate to remotely monitor oncology trials, ensuring adherence to protocols, GCP, and regulatory requirements. This role supports sites worldwide from a home office, with emphasis on rigorous SDV and data integrity.

You will train site staff, manage relationships, prepare monitoring reports, and coordinate with internal teams and vendors. A life-science degree and 5+ years of CRA experience, especially in oncology, are required.

Qualifications

• Bachelor's degree in life science, nursing, or related field; advanced degree preferred.
• Minimum of 5 years as a CRA with oncology focus.
• Strong knowledge of ICH GCP, regulations, and monitoring processes.

Responsibilities

• Perform remote monitoring of trial sites to ensure protocol compliance and data integrity.
• Oversee SDV via remote review of EHRs and study documents.
• Build and maintain site relationships; train investigators and staff.
• Identify issues and implement CAPAs to ensure trial quality.
• Maintain regulatory documentation and drug accountability at sites.
• Coordinate site initiation, interim monitoring, and site close-out remotely.
• Prepare monitoring reports and participate in investigator meetings.
• Act as a primary contact for sites and internal/external teams.

Skills

Remote monitoring

EDC systems

Oncology trials

ICH GCP knowledge

Time management

Communication

Education

Bachelor's degree in life science

Advanced degree preferred

Job description

About the Role

Our client, a leading global biopharmaceutical company, is seeking a highly experienced Senior Clinical Research Associate (CRA) to remotely support their groundbreaking oncology clinical trials. This role is critical in ensuring the successful execution of studies that bring innovative cancer treatments to patients worldwide. The Senior CRA will be responsible for monitoring clinical trial sites, ensuring adherence to protocols, regulatory requirements, and Good Clinical Practice (GCP) guidelines. This is a fully remote position, offering flexibility while requiring a high degree of self-discipline and proactive engagement. You will work with cutting-edge therapies and contribute to life-changing advancements in cancer care from anywhere in the world, with a specific focus on research relevant to populations potentially served by services in Limpopo , even though the role is remote.

Key Responsibilities

• Perform remote monitoring of clinical trial sites to ensure compliance with study protocols, SOPs, and regulatory requirements (e.g., FDA, EMA, ICH GCP).
• Ensure accurate, complete, and timely source data verification (SDV) through remote review of electronic health records and other study documents.
• Manage site relationships, providing training and ongoing support to investigators and site staff.
• Oversee site performance, identify potential issues, and implement corrective and preventative actions (CAPAs).
• Ensure timely drug accountability and regulatory documentation at study sites.
• Facilitate site initiation, interim monitoring visits, and site closure activities remotely.
• Prepare and present monitoring reports and participate in investigator meetings.
• Maintain comprehensive study documentation and ensure data integrity.
• Act as a key point of contact for sites, internal study teams, and external vendors.

Requirements

• Bachelor's degree in a life science, nursing, or related field; advanced degree preferred.
• A minimum of 5 years of experience as a Clinical Research Associate (CRA), with a significant portion focused on oncology trials.
• Extensive knowledge of ICH GCP guidelines, clinical trial regulations, and monitoring processes.
• Proven experience with remote monitoring techniques and electronic data capture (EDC) systems.
• Strong understanding of oncology drug development and trial complexities.
• Excellent organizational, time management, and problem-solving skills.
• Exceptional communication, interpersonal, and negotiation skills.
• Ability to work independently, manage multiple priorities, and meet strict deadlines in a remote setting.
• Fluency in English is essential; proficiency in other languages is a plus.

Benefits

• This is a contract position offering a competitive hourly rate or project-based compensation.
• As a remote employee, you will have the flexibility to work from home.
• Our client provides opportunities for professional development, exposure to innovative clinical trials, and the chance to contribute significantly to oncology research.
• You will be part of a dynamic global team dedicated to improving patient outcomes through advanced clinical research.