Senior Clinical Data Scientist – R Shiny

ICON Strategic Solutions; Johannesburg; On-site; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Various annual leave entitlements

Health insurance offerings

Competitive retirement planning

Global Employee Assistance Programme (

Life assurance

Flexible country-specific optional ben

Well-being and family support

Job summary

ICON Strategic Solutions is seeking a Senior Clinical Data Scientist to analyse clinical trial data and support the statistical analysis process, delivering high-quality results.

You will transform complex data into intuitive applications and analytical solutions, collaborating with statisticians, data managers and programmers to advance R and Shiny capabilities across projects.

Qualifications

• 5+ years in statistical programming, clinical data analysis or Real World Evidence.
• Experience with R Shiny app development and dashboards.
• Knowledge of CDISC standards (SDTM/ADaM) and clinical trial data.

Responsibilities

• Design and develop engaging R Shiny applications and dashboards for study monitoring and evidence generation.
• Use R and advanced statistical techniques to transform complex datasets into meaningful insights.
• Build scalable, well-documented solutions with a focus on performance and UX.
• Collaborate with cross-functional teams to ensure CDISC standards and internal quality compliance.
• Share expertise, contribute to best practices and automation initiatives across the team.

Skills

R

R Shiny

Statistical programming

CDISC SDTM/ADaM

Git & CRAN

Data wrangling

Python/SAS (nice-to-have)

Cloud technologies

Education

Statistics/Mathematics/CS/Life Sciences degree

Tools

ggplot2

Plotly

Posit Connect/Shiny Server

Job description

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.

As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

As a Senior Clinical Data Scientist at ICON, you will analyse clinical trial data and support the statistical analysis process to ensure high-quality results.

In this role, you will have the opportunity to transform complex clinical and real-world data into intuitive applications and analytical solutions that help answer meaningful clinical questions and support evidence-based decision‑making. You will work alongside statisticians, data managers, programmers and clinical colleagues, while helping shape how we use R and modern analytical technologies across our projects.

What You Will Do

• Design and develop engaging R Shiny applications, dashboards and visualisations to support clinical study monitoring, data review, safety analysis and evidence generation.
• Use R and advanced statistical techniques to transform complex clinical and real-world datasets into meaningful and accessible insights.
• Build scalable, modular and well-documented solutions, while continuously improving performance, usability and user experience.
• Partner with cross-functional colleagues to ensure solutions follow relevant CDISC standards, regulatory requirements and internal quality standards.
• Share your expertise in R and R Shiny, contribute to best practices and automation initiatives, and support the development of colleagues across the team.

Your Profile

• Around 5+ years of relevant experience in statistical programming, clinical data analysis, Real World Evidence/HTA, Medical Affairs or evidence generation, ideally within a pharmaceutical, biotech or CRO environment.
• Strong hands-on experience with R and R Shiny, including application development, interactive dashboards, visualisation and tools such as ggplot2 or Plotly.
• Good knowledge of the broader R ecosystem, which may include R packages, Git, CRAN, data wrangling and statistical methodologies.
• Experience working with clinical or healthcare data. Knowledge of CDISC standards such as SDTM and ADaM, TLFs, or Phase IIIb/IV clinical trials would be particularly valuable.
• A degree in Statistics, Mathematics, Computer Science, Life Sciences or a related discipline, or equivalent relevant experience. Knowledge of Python, SAS, cloud technologies, Posit Connect/Shiny Server or Real World Data is welcome but not essential.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here.

What ICON Can Offer You

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent. In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our Benefits Examples Include

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.