Senior Clinical Data Manager — Hybrid, Growth & Impact

Placements24; Randburg; Hybrid; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Health insurance

Retirement plan with employer matching

Hybrid work model

Job summary

Placements24 is seeking an experienced Senior Clinical Data Manager for a prominent CRO in Randburg. You will oversee database design, development, and data management for complex multicenter trials, ensuring accuracy, integrity, and regulatory compliance from setup to database lock.

You will lead DM activities, develop DMPs/CRFs, and collaborate with biostatistics and programming to support regulatory submissions and research outputs. Hybrid work arrangements are available.

Qualifications

• Minimum 7 years of progressive clinical data management experience.
• Experience with EDC systems (Medidata Rave, Oracle Clinical, Inform).
• Strong knowledge of CDISC SDTM/ CDASH data standards.

Responsibilities

• Lead data management activities for multicenter trials from design to database lock.
• Develop and review DMPs, CRFs, and CRF completion guidelines.
• Ensure data quality, validation, and regulatory compliance (ICH-GCP).
• Mentor junior data management staff and collaborate with cross-functional teams.

Skills

Data management

Leadership

Analytical thinking

Communication

Problem solving

Prioritization

Education

Bachelor's degree in life sciences/related field

Advanced degree preferred

Tools

Medidata Rave

Oracle Clinical

Inform

SQL

Job description

Placements24 is seeking an experienced Senior Clinical Data Manager for a prominent CRO in Randburg. You will oversee database design, development, and data management for complex multicenter trials, ensuring accuracy, integrity, and regulatory compliance from setup to database lock.

You will lead DM activities, develop DMPs/CRFs, and collaborate with biostatistics and programming to support regulatory submissions and research outputs. Hybrid work arrangements are available.