Senior Bioinformatician - Clinical Data Analysis

Placements24; Polokwane; Hybrid; ZAR 900,000 - 1,200,000; Full time

Benefits offered by this job

Annual performance bonus

Health, dental, vision insurance

Paid time off

Job summary

Placements24 is recruiting a Senior Bioinformatician for our client in Polokwane to lead analysis of clinical genomic datasets and drive insights for diagnostic and therapeutic advancements.

You will develop pipelines for omics data, perform statistical analyses, and collaborate with clinicians and researchers to interpret results. A PhD or Master's in a quantitative field and 5+ years of bioinformatics experience with clinical data are required.

Qualifications

• PhD or Master's in Bioinformatics, Computer Science, Statistics, Computational Biology, or related field.
• Minimum of 5 years of relevant experience in bioinformatics, with a focus on clinical data analysis.
• Strong programming skills in Python, R, or Perl.
• Proficiency in statistical analysis and machine learning techniques.
• Experience with clinical trial data and regulatory requirements is advantageous.

Responsibilities

• Develop and implement bioinformatics pipelines for clinical genomic, transcriptomic, and proteomic data.
• Perform statistical analysis on large clinical datasets to identify biomarkers and stratify populations.
• Collaborate with clinical research teams to design studies and interpret results.
• Integrate diverse data sources including EHR, imaging, and omics data.
• Develop and maintain data management systems for clinical research data.
• Create visualizations and reports for technical and non-technical stakeholders.
• Ensure data quality, integrity and regulatory compliance.
• Stay updated with bioinformatics advances and clinical informatics.
• Mentor junior bioinformaticians and contribute to knowledge sharing.
• Troubleshoot challenges and propose innovative solutions.

Skills

Python

R

Perl

Machine learning

Data visualization

Education

PhD/ Masters in Bioinformatics

Tools

Bioconductor

Nextflow

SQL

Job description

About the Role

Our client, a forefront institution in scientific research and development, is seeking an experienced Senior Bioinformatician to join their dynamic team in Polokwane . This critical role involves the analysis of complex clinical datasets to derive meaningful insights that can drive diagnostic and therapeutic advancements. The ideal candidate will possess a robust understanding of bioinformatics principles, statistical analysis, and programming, coupled with significant experience in handling clinical trial data and patient-derived omics data. You will collaborate closely with clinicians, researchers, and data scientists to interpret results and contribute to impactful scientific endeavors. We are committed to fostering an environment of continuous learning and innovation. The Polokwane location offers a growing scientific community and access to significant healthcare initiatives, making it an exciting place to advance one's career in medical research.

Key Responsibilities

• Develop and implement bioinformatics pipelines for the analysis of clinical genomic, transcriptomic, and proteomic data.
• Perform statistical analysis on large clinical datasets to identify biomarkers, predict patient outcomes, and stratify patient populations.
• Collaborate with clinical research teams to design studies, analyze data, and interpret results.
• Integrate diverse data sources, including electronic health records, imaging data, and omics data.
• Develop and maintain robust data management systems and databases for clinical research data.
• Create visualizations and reports to communicate complex findings to both technical and non-technical stakeholders.
• Ensure data quality, integrity, and compliance with regulatory standards (e.g., HIPAA, GDPR).
• Stay abreast of the latest advancements in bioinformatics, clinical informatics, and relevant biological fields.
• Mentor junior bioinformaticians and contribute to team knowledge sharing.
• Troubleshoot analytical challenges and propose innovative solutions.

Requirements

• PhD or Master's degree in Bioinformatics, Computer Science, Statistics, Computational Biology, or a related quantitative field.
• Minimum of 5 years of relevant experience in bioinformatics, with a focus on clinical data analysis.
• Strong programming skills in languages such as Python, R, or Perl.
• Proficiency in statistical analysis and machine learning techniques.
• Experience with common bioinformatics tools and databases.
• Familiarity with clinical trial processes and regulatory requirements is highly advantageous.
• Experience handling sensitive clinical data and ensuring data privacy.
• Excellent communication, presentation, and interpersonal skills.
• Ability to work independently and as part of a multidisciplinary team.
• Must possess the legal right to work in South Africa .

Benefits

• Our client offers a competitive salary, commensurate with experience, along with annual performance bonuses.
• Comprehensive health, dental, and vision insurance are provided.
• Generous paid time off, including vacation and sick leave, is standard.
• Opportunities for professional development, including workshops, training, and conference attendance, are readily available.
• Access to advanced computational resources and diverse clinical datasets is assured.
• This role is based in Polokwane , offering a unique opportunity to contribute to significant healthcare research within a developing scientific hub.
• Relocation assistance may be provided.