Research Scientist - Molecular Diagnostics

Placements24; Kempton Park; On-site; ZAR 900,000 - 1,300,000; Full time

Benefits offered by this job

Salary bonus

Healthcare coverage

Paid leave

Learning opportunities

Lab equipment access

Culture of innovation

Wellness programs

Career advancement

Job summary

Placements24 is seeking a Research Scientist to join its Molecular Diagnostics team in Gauteng. The role focuses on designing, developing, and validating novel diagnostic assays for early disease detection and monitoring, using PCR, qPCR, ddPCR, and NGS.

You will lead experiments, analyse data, and generate reports to drive patient outcomes. A PhD or MSc in life sciences plus 4+ years of hands-on experience in assay development is required, with GLP/regulatory exposure preferred.

Qualifications

• PhD or Master's in molecular biology or related field.
• At least 4 years of hands-on experience in developing and validating molecular diagnostic assays.
• Strong knowledge of molecular biology techniques (PCR, qPCR, nucleic acid isolation).
• NGS library prep and sequencing experience desirable.
• Proficient in data analysis and statistics.
• Excellent documentation and record-keeping.
• Ability to manage multiple projects and work independently.
• Strong communication and presentation skills.
• Experience in regulated environments (ISO CLIA) is a plus.

Responsibilities

• Develop and optimise molecular diagnostic assays via PCR, qPCR, ddPCR, and NGS.
• Design and execute experiments to validate assay performance.
• Analyse data, interpret results, and generate reports.
• Troubleshoot technical issues during assay development.
• Collaborate with cross-functional teams to progress projects.
• Support regulatory submissions and scientific publications.
• Maintain GLP-compliant lab records.
• Stay updated with literature and tech advances.
• Characterise and validate novel biomarkers.

Skills

PCR

qPCR

ddPCR

NGS

Molecular biology

Data analysis

Statistics

Documentation

Independent work

Communication

Education

PhD or Master's in Molecular Biology/Related Life Sciences

Tools

NGS platforms

Data analysis software

Statistical tools

Job description

About the Role

Our client, a leading pharmaceutical research and development company, is seeking a dedicated Research Scientist to join their innovative Molecular Diagnostics team in Tembisa, Gauteng. This critical role will involve the design, development, and validation of novel diagnostic assays for the early detection and monitoring of diseases. You will be at the forefront of scientific discovery, contributing to projects that aim to significantly improve patient outcomes through precise and timely diagnostic solutions. The role requires a deep understanding of molecular biology techniques and a passion for translating scientific findings into tangible diagnostic tools. You will be part of a highly collaborative team working in a state-of-the‑art laboratory environment. This position offers an exceptional opportunity to shape the future of diagnostics within a company committed to scientific excellence and global health.

Key Responsibilities

• Develop and optimise molecular diagnostic assays, including PCR, qPCR, ddPCR, and next‑generation sequencing (NGS) based methods.
• Design and execute experiments to validate assay performance, including sensitivity, specificity, accuracy, and reproducibility.
• Analyse experimental data, interpret results, and generate comprehensive reports.
• Troubleshoot and resolve technical issues that may arise during assay development and validation.
• Collaborate with cross‑functional teams, including product development, manufacturing, and clinical affairs, to ensure seamless project progression.
• Contribute to the preparation of regulatory submissions and scientific publications.
• Maintain accurate and detailed laboratory records in compliance with Good Laboratory Practices (GLP).
• Stay updated with the latest scientific literature and technological advancements in molecular diagnostics.
• Characterise and validate novel biomarkers for diagnostic applications.

Requirements

• Ph.D. or Master's degree in Molecular Biology, Biochemistry, Genetics, or a related life science discipline.
• Minimum of 4 years of hands‑on experience in developing and validating molecular diagnostic assays.
• Extensive knowledge and practical experience with various molecular biology techniques (PCR, qPCR, nucleic acid isolation, etc.).
• Experience with NGS library preparation and sequencing platforms is highly desirable.
• Proficiency in data analysis software and statistical methods.
• Strong understanding of assay principles and validation strategies.
• Excellent organisational, documentation, and record‑keeping skills.
• Ability to work independently and manage multiple projects simultaneously.
• Effective communication and presentation skills, both written and verbal.
• Experience working in a regulated environment (e.g., ISO 13485, CLIA) is an advantage.

Benefits

• Competitive annual salary and performance‑based bonuses.
• Comprehensive medical, dental, and vision coverage.
• Generous annual leave and public holiday allocation.
• Opportunities for continuous learning and professional growth, including workshops and conferences.
• Access to advanced laboratory equipment and resources.
• A supportive and dynamic team culture focused on innovation.
• Employee wellness programs and initiatives.
• Potential for long‑term career advancement within a growing organisation.