Senior Molecular Biologist - Genomics Research

Placements24; Johannesburg; Hybrid; ZAR 900,000 - 1,200,000; Full time

Benefits offered by this job

Comprehensive health insurance

Generous retirement fund contribution

Professional development opportunities

State-of-the-art facilities

Johannesburg location with good access

Job summary

Placements24 is seeking a Senior Molecular Biologist for their bioscience research organization in Johannesburg. You will lead the design, execution, and analysis of complex genomics experiments to advance understanding of human genetics and disease mechanisms.

The role requires a PhD or Master’s, 5+ years in genomics, and strong skills in PCR, qPCR, NGS library prep, and data analysis with R, Python, or SPSS. You’ll mentor junior staff and collaborate across teams.

Qualifications

• Ph.D. or Master’s in Molecular Biology or related field.
• At least 5 years of hands-on genomics R&D experience.
• Proficient in PCR, qPCR and NGS library prep.
• Skilled in data analysis with R, Python, or SPSS.
• Strong problem-solving and meticulous attention to detail.
• Excellent communication and mentoring abilities.
• GLP familiarity is a plus.

Responsibilities

• Design and execute molecular biology experiments (DNA/RNA extraction, PCR, qPCR).
• Develop and optimize novel genomic assays and protocols.
• Analyze data using bioinformatics tools and statistics.
• Troubleshoot experiments to ensure project progression.
• Contribute to writing research papers and grant proposals.
• Mentor junior staff and supervise lab activities.
• Maintain detailed lab notebooks and ensure safety and quality standards.
• Collaborate with cross-functional teams (bioinformaticians, clinicians, researchers).
• Stay updated on advances in molecular biology and genomics.

Skills

PCR

qPCR

NGS library prep

Genotyping

DNA extraction

RNA extraction

Bioinformatics

R

Python

SPSS

Education

PhD in Molecular Biology

Master's in Molecular Biology

Tools

Python

R

SPSS

Bioinformatics tools

Job description

About the Role Our client, a leading bioscience research organization, is seeking a highly motivated and experienced Senior Molecular Biologist to join their innovative team in Johannesburg, Gauteng. This pivotal role will contribute to groundbreaking research and development projects focused on advancing our understanding of human genetics and disease mechanisms. The successful candidate will be instrumental in designing, executing, and analyzing complex experiments, ultimately driving scientific discovery and contributing to potential therapeutic interventions. This position offers a unique opportunity to work at the forefront of genomic research within a dynamic and collaborative environment.

Key Responsibilities

• Design and execute advanced molecular biology experiments, including DNA/RNA extraction, PCR, qPCR, sequencing library preparation, and genotyping.
• Develop and optimize novel molecular assays and protocols for genomic analysis.
• Perform data analysis using bioinformatics tools and statistical methods, interpreting results accurately.
• Troubleshoot experimental issues and implement effective solutions to ensure project progression.
• Contribute to the writing of research papers, grant proposals, and internal reports.
• Supervise and mentor junior research staff, fostering a culture of scientific excellence.
• Maintain detailed laboratory notebooks and ensure compliance with safety and quality standards.
• Collaborate effectively with cross-functional teams, including bioinformaticians, clinicians, and other research scientists.
• Stay abreast of the latest advancements in molecular biology, genomics, and related fields.

Requirements

• Ph.D. or Master's degree in Molecular Biology, Genetics, Biochemistry, or a related field.
• Minimum of 5 years of hands‑on experience in a research and development setting, with a strong focus on genomics.
• Proven expertise in a broad range of molecular biology techniques (PCR, qPCR, NGS library prep, etc.).
• Proficiency in data analysis software (e.g., R, Python, SPSS) and bioinformatics tools.
• Excellent problem‑solving skills and a meticulous attention to detail.
• Strong written and verbal communication skills, with the ability to present complex scientific information clearly.
• Demonstrated ability to work independently and as part of a team.
• Experience in a supervisory or mentorship role is highly desirable.
• Familiarity with Good Laboratory Practice (GLP) is a plus.

Benefits

• This includes a comprehensive health insurance plan, a generous retirement fund contribution, and opportunities for professional development and further education.
• Employees benefit from access to state‑of‑the‑art laboratory facilities and a supportive work environment that encourages innovation and collaboration.
• Located in the vibrant city of Johannesburg, the role also provides access to a rich cultural and social scene, with excellent transport links and amenities.