Research Scientist - Medicinal Chemistry

Placements24; Gqeberha; Hybride; ZAR 900 000 - 1 300 000; Plein temps

Avantages offerts par ce poste

Bonus program

Health benefits

Professional development

Laboratory access

Collaborative environment

Résumé du poste

Placements24 in Port Elizabeth is seeking a Research Scientist specialized in Medicinal Chemistry to drive the design, synthesis, and optimization of small molecules for drug discovery.

The role requires a PhD in Medicinal Chemistry or related field, strong SAR insight, and expertise in modern analytical techniques. You will work in a collaborative, interdisciplinary team focused on advancing therapeutic candidates and reporting synthesis data.

Qualifications

• Ph.D. in Medicinal Chemistry, Organic Chemistry, or related field.
• Demonstrated experience in the synthesis of complex organic molecules.
• Strong understanding of SAR principles and drug discovery processes.
• Proficiency in modern analytical techniques for compound characterization.
• Ability to work effectively in a collaborative, team-oriented research environment.
• Excellent problem-solving skills and a commitment to scientific rigor.

Responsabilités

• Design and synthesize novel small molecules with potential therapeutic activity using advanced organic chemistry techniques.
• Optimize lead compounds through iterative structure-activity relationship (SAR) studies.
• Characterize synthesized compounds using analytical methods such as NMR, LC-MS, and HPLC.
• Collaborate with biologists and pharmacologists to evaluate the efficacy and safety of drug candidates.
• Maintain detailed laboratory notebooks and prepare reports on synthesis and characterization data.
• Stay current with advances in medicinal chemistry and drug discovery technologies.

Connaissances

Medicinal chemistry

Synthesis of complex molecules

SAR principles

Analytical techniques

Team collaboration

Formation

Ph.D. in Medicinal Chemistry

Outils

NMR

LC-MS

HPLC

Description du poste

About the Role

Our client is seeking a talented Research Scientist specializing in Medicinal Chemistry to join their dynamic team in Port Elizabeth . This role is crucial for the discovery and development of novel therapeutic agents, focusing on the design, synthesis, and optimization of small molecules. You will work collaboratively within a multidisciplinary team, contributing your expertise in synthetic organic chemistry to identify and develop promising drug candidates that address unmet medical needs.

Key Responsibilities

• Design and synthesize novel small molecules with potential therapeutic activity using advanced organic chemistry techniques.
• Optimize lead compounds through iterative structure-activity relationship (SAR) studies.
• Characterize synthesized compounds using analytical methods such as NMR, LC-MS, and HPLC.
• Collaborate with biologists and pharmacologists to evaluate the efficacy and safety of drug candidates.
• Maintain detailed laboratory notebooks and prepare reports on synthesis and characterization data.
• Stay current with advances in medicinal chemistry and drug discovery technologies.

Requirements

• Ph.D. in Medicinal Chemistry, Organic Chemistry, or a related field.
• Demonstrated experience in the synthesis of complex organic molecules.
• Strong understanding of SAR principles and drug discovery processes.
• Proficiency in modern analytical techniques for compound characterization.
• Ability to work effectively in a collaborative, team-oriented research environment.
• Excellent problem-solving skills and a commitment to scientific rigor.

Benefits

• Competitive annual salary and a structured bonus program.
• Comprehensive health and wellness benefits.
• Opportunities for professional development and attendance at scientific conferences.
• Access to modern synthetic chemistry laboratories and analytical instrumentation.
• A supportive and collaborative work environment focused on innovation in drug discovery.