Research Fellow - Pharmaceutical Chemistry

Placements24; Durban; Sur place; ZAR 900 000 - 1 200 000; Plein temps

Avantages offerts par ce poste

Competitive salary

Health insurance

On-site lab access

Résumé du poste

WhatJobs Direct in Durban, KwaZulu-Natal, ZA, is recruiting a Research Fellow to advance our drug discovery program by designing, synthesizing, and optimizing novel small molecules with therapeutic potential.

This hands-on role requires expertise in modern synthetic organic chemistry, including asymmetric and heterocyclic techniques, and you will work with medicinal chemists, biologists, and pharmacologists to reach project milestones.

Qualifications

• PhD required with postdoctoral or industry experience in synthetic organic chemistry.
• Hands-on expertise with modern synthetic techniques including asymmetric synthesis and heterocycles.
• Proficiency in spectroscopic methods (NMR, MS, HPLC, IR) for characterization.
• Strong understanding of medicinal chemistry and drug discovery processes.

Responsabilités

• Design and synthesize novel organic compounds for drug discovery programs.
• Develop and optimize synthetic routes for target molecules, ensuring efficiency and scalability.
• Characterize synthesized compounds using NMR, MS, HPLC, and IR.

Connaissances

Organic synthesis

Asymmetric synthesis

Heterocyclic chemistry

Spectroscopic analysis

SAR studies

Drug discovery

Formation

PhD in Organic Chemistry or Medicinal Chemistry

Description du poste

About the Role

Our client, WhatJobs Direct, is recruiting for a highly skilled Research Fellow to join their innovative Pharmaceutical Chemistry department in Durban, KwaZulu-Natal, ZA . This position is crucial for advancing our drug discovery and development pipeline. You will be responsible for the synthesis, characterization, and optimization of novel small molecules with therapeutic potential. This hands-on laboratory role requires a deep understanding of organic chemistry principles and a proven ability to design and execute complex synthetic routes. You will work closely with medicinal chemists, biologists, and pharmacologists to achieve project milestones. The ideal candidate is passionate about creating new chemical entities and possesses excellent analytical skills, meticulous experimental technique, and a strong commitment to safety and quality in a fully on-site laboratory setting. This is an exceptional opportunity to contribute to impactful pharmaceutical research in a dynamic environment.

Key Responsibilities

• Design and synthesize novel organic compounds for drug discovery programs.
• Develop and optimize synthetic routes for target molecules, ensuring efficiency and scalability.
• Characterize synthesized compounds using a variety of analytical techniques, including NMR, Mass Spectrometry, and HPLC.
• Conduct structure-activity relationship (SAR) studies to guide lead optimization efforts.
• Collaborate with medicinal chemists to identify promising chemical scaffolds and lead compounds.
• Work closely with biologists and pharmacologists to test and evaluate the efficacy and safety of synthesized compounds.
• Troubleshoot synthetic challenges and develop innovative solutions.
• Maintain accurate and detailed laboratory notebooks and research records.
• Stay abreast of the latest advancements in synthetic organic chemistry and medicinal chemistry.
• Ensure adherence to all laboratory safety protocols and regulatory guidelines within the Durban, KwaZulu-Natal, ZA facility.

Requirements

• PhD in Organic Chemistry, Medicinal Chemistry, or a closely related field.
• Minimum of 3 years of postdoctoral or industrial research experience in synthetic organic chemistry, preferably within the pharmaceutical sector.
• Extensive hands-on experience in modern synthetic organic chemistry techniques, including asymmetric synthesis and heterocyclic chemistry.
• Proficiency in spectroscopic techniques for compound characterization (NMR, MS, HPLC, IR).
• Strong understanding of medicinal chemistry principles and drug discovery processes.
• Proven ability to design and execute multi-step synthetic sequences.
• Excellent problem-solving skills and meticulous attention to detail.
• Strong laboratory and practical skills, with a commitment to safety.
• Ability to work independently and collaboratively within a research team.
• Excellent written and verbal communication skills.

Benefits

• Competitive salary and potential for performance-based bonuses.
• Opportunity to work on cutting-edge drug discovery projects.
• Comprehensive health, dental, and vision insurance.
• Access to state-of-the-art synthesis and analytical laboratories.
• Professional development opportunities and support for attending scientific conferences.
• Retirement savings plan.
• Generous paid time off and holidays.
• A collaborative and scientifically stimulating work environment.
• Contribution to the development of potentially life-saving medicines.
• On-site position with full access to facilities and equipment.