Research Chemist - Pharmaceutical Development

Placements24; Gqeberha; Hybrid; ZAR 600,000 - 900,000; Full time

Benefits offered by this job

Bonus program

Career growth

Flexible remote

Health & wellness

Job summary

Placements24 is seeking an innovative Research Chemist to join a growing Pharmaceutical Development team in Port Elizabeth with a remote capacity. You will design, synthesize, and characterize novel chemical entities with therapeutic potential, contributing to the drug discovery pipeline from hit identification through lead optimization.

The ideal candidate will be a highly skilled synthetic organic chemist, capable of working independently in a virtual research environment and collaborating

Qualifications

• PhD in Organic Chemistry or Medicinal Chemistry required.
• Minimum of 4 years of postdoctoral or industrial experience in pharmaceutical R&D.
• Extensive hands-on experience in synthetic organic chemistry and purification.
• Proficiency in analytical characterization methods (NMR, MS, HPLC).

Responsibilities

• Design and synthesize novel organic molecules using diverse methodologies.
• Purify and characterize compounds using NMR, MS, and HPLC.
• Develop structure-activity relationships (SAR) through iterative synthesis and biological testing.
• Optimize lead compounds for potency, selectivity, and PK properties.
• Collaborate with project teams to define synthetic strategies and milestones.

Skills

Synthetic Organic Chemistry

Purification Techniques

Analytical Characterization

SAR/Lead Optimization

Education

PhD in Organic Chemistry or Medicinal Chemistry

Tools

NMR

Mass Spectrometry

HPLC

Job description

About the Role

Our client is seeking an innovative Research Chemist to join their expanding Pharmaceutical Development team in Port Elizabeth , operating in a remote capacity. This role is crucial for the design, synthesis, and characterization of novel chemical entities with therapeutic potential. You will play a key part in the drug discovery pipeline, from hit identification through lead optimization, working in close collaboration with computational chemists, biologists, and pharmacologists. The ideal candidate is a highly skilled synthetic organic chemist with a passion for discovering new medicines and a proven ability to work effectively and independently in a virtual research environment, contributing to the development of next-generation pharmaceuticals.

Key Responsibilities

• Design and synthesize novel organic molecules using a wide range of synthetic methodologies.
• Purify and characterize synthesized compounds using techniques such as NMR, Mass Spectrometry, and HPLC.
• Develop structure-activity relationships (SAR) through iterative chemical synthesis and biological testing.
• Optimize lead compounds for improved potency, selectivity, and pharmacokinetic properties.
• Collaborate with project teams to define synthetic strategies and achieve project milestones.

Requirements

• Ph.D. in Organic Chemistry or Medicinal Chemistry.
• Minimum of 4 years of postdoctoral or industrial experience in pharmaceutical research .
• Extensive hands-on experience in synthetic organic chemistry and purification techniques.
• Proficiency in analytical characterization methods (NMR, MS, HPLC, etc.).
• Strong problem-solving abilities and a creative approach to complex synthetic challenges.

Benefits

• Highly competitive salary and bonus structure.
• Significant opportunities for career advancement within a leading pharmaceutical company.
• Flexible remote working environment.
• Comprehensive health and wellness benefits.
• Contribution to the development of innovative medicines that improve patient lives.