Research Chemist - Organic Synthesis

Placements24; Mossel Bay; Hybrid; ZAR 700,000 - 1,000,000; Full time

Benefits offered by this job

Competitive salary

Health insurance

Hybrid work arrangement

Professional development opportunities

Paid time off

Job summary

Placements24 is seeking a Research Chemist in Mossel Bay to design and execute multi-step synthetic routes for novel organic molecules. You will perform a variety of reactions, purify products, and characterize compounds using NMR, MS, IR, and related techniques. Collaboration with medicinal chemists and biologists will be essential to support drug discovery.

The ideal candidate holds a Ph.D. or Master's in Organic/Medicinal Chemistry with a strong publication record and experience in

Qualifications

• Ph.D. or Master's in Organic Chemistry, Medicinal Chemistry, or closely related field.
• Demonstrated experience in synthetic organic chemistry with a strong publication record or equivalent.
• Proficiency in a wide range of organic reactions and purification techniques.
• Experience with analytical techniques for compound characterization (NMR, MS).
• Ability to design synthetic routes and troubleshoot experimental problems.
• Strong organizational skills and attention to detail.
• Excellent communication and teamwork abilities.
• Willingness to work effectively in a hybrid environment with lab and remote responsibilities.
• Experience in pharmaceutical R&D is highly desirable.

Responsibilities

• Design and execute multi-step synthetic routes for target organic molecules.
• Perform various organic reactions, including coupling, asymmetric synthesis, and heterocyclic chemistry.
• Purify reaction products using chromatography and crystallization techniques.
• Characterize synthesized compounds using NMR, Mass Spectrometry (MS), IR, and other methods.
• Optimize reaction conditions to improve yield, purity, and efficiency.
• Collaborate with medicinal chemists and biologists to support drug discovery programs.
• Maintain accurate and detailed laboratory records.
• Stay updated on latest developments in synthetic organic chemistry.
• Troubleshoot synthetic challenges and propose alternative strategies.
• Contribute to preparation of research reports and publications.

Skills

Synthetic organic chemistry

Publication record

Analytical skills

Education

Ph.D. in Organic/Medicinal Chemistry

Master's in Organic/Medicinal Chemistry

Tools

NMR

Mass Spectrometry (MS)

IR

HPLC

Job description

About the Role

Our client, a dynamic pharmaceutical research company, is seeking a talented Research Chemist with expertise in organic synthesis to join their team in Mossel Bay, Western Cape, ZA . This role offers a hybrid work model, combining valuable laboratory time with the flexibility of remote work. You will be instrumental in the design and execution of synthetic routes for novel small molecules, contributing to the discovery and development of new therapeutic agents. This position requires a strong foundation in modern synthetic organic chemistry, a meticulous approach to experimentation, and a passion for medicinal chemistry. The ideal candidate will be a creative problem-solver, capable of navigating complex synthetic challenges and contributing to a collaborative research environment. We are looking for an individual eager to make a significant impact on drug discovery efforts.

Key Responsibilities

• Design and execute multi-step synthetic routes for target organic molecules.
• Perform various organic reactions, including coupling reactions, asymmetric synthesis, and heterocyclic chemistry.
• Purify reaction products using chromatography (column, HPLC) and crystallization techniques.
• Characterize synthesized compounds using NMR, Mass Spectrometry, IR, and other analytical methods.
• Optimize reaction conditions to improve yield, purity, and efficiency.
• Collaborate with medicinal chemists and biologists to support drug discovery programs.
• Maintain accurate and detailed laboratory records.
• Stay updated on the latest developments in synthetic organic chemistry.
• Troubleshoot synthetic challenges and propose alternative strategies.
• Contribute to the preparation of research reports and publications.

Requirements

• Ph.D. or Master's degree in Organic Chemistry, Medicinal Chemistry, or a closely related field.
• Demonstrated experience in synthetic organic chemistry, with a strong publication record or equivalent research experience.
• Proficiency in a wide range of organic reactions and purification techniques.
• Experience with analytical techniques for compound characterization (NMR, MS).
• Ability to design synthetic routes and troubleshoot experimental problems.
• Strong organizational skills and attention to detail.
• Excellent communication and teamwork abilities.
• Willingness to work effectively in a hybrid environment, balancing lab work with remote responsibilities.
• Experience in pharmaceutical R&D is highly desirable.

Benefits

• Our client offers a competitive salary, comprehensive health insurance, and participation in a generous bonus scheme.
• Employees have access to modern laboratory facilities and advanced instrumentation.
• Opportunities for professional development, including attending scientific conferences, are provided.
• We offer a supportive and collaborative work culture with a hybrid work arrangement that balances on-site and remote work, fostering both productivity and work-life balance.
• Paid time off and opportunities for career growth are included.