Production Pharmacist

PSMP; Gauteng; On-site; ZAR 650,000 - 900,000; Full time

Job summary

PSMP is seeking experienced Production Pharmacists to provide pharmaceutical and technical oversight of manufacturing operations in accordance with GMP, SAHPRA requirements, approved procedures and quality standards.

The role involves overseeing manufacturing and packaging, reviewing batch records, drafting SOPs, investigating deviations and CAPA, supporting validation activities, and ensuring inspections and audits are addressed with a continuous improvement mindset.

Qualifications

• Bachelor of Pharmacy (BPharm) and SAPC registration.
• 3–5 years' pharmaceutical manufacturing experience.
• Experience in solid dosage, liquids, creams or sterile environments.
• Familiar with GMP systems, regulatory inspections, SOPs and document control.
• Knowledge of SAHPRA regulations and PIC/S GMP guidelines.
• Experience with batch documentation, deviations, CAPA and root cause analysis.
• Understanding of risk management and data integrity in production.
• Strong leadership and decision-making capabilities.

Responsibilities

• Oversee pharmaceutical manufacturing and packaging operations for GMP compliance.
• Monitor production activities, line clearance, material segregation and equipment verification.
• Review batch records, material reconciliations and production documentation for accuracy.
• Draft and implement SOPs, work instructions and batch records.
• Investigate deviations, CAPA, root cause analysis and corrective actions.
• Support process validation, cleaning validation and equipment qualification.
• Identify continuous improvement initiatives to enhance efficiency and quality.
• Provide GMP/SOP/data integrity training and ensure competency records.
• Assist audits and SAHPRA inspections and address findings.
• Ensure production areas meet OHSE requirements and remain inspection-ready.

Skills

Leadership

Problem-solving

Decision-making

Communication

Analytical thinking

Stakeholder engagement

Ethical conduct

Continuous improvement mindset

Education

BPharm degree

SAPC registration

Job description

Our client in the pharmaceutical manufacturing industry is seeking experienced Production Pharmacists to provide pharmaceutical and technical oversight of manufacturing operations, ensuring that products are manufactured, packaged and documented in accordance with Good Manufacturing Practice (GMP), SAHPRA requirements, approved procedures and quality standards.

Key Responsibilities

• Oversee pharmaceutical manufacturing and packaging operations, ensuring compliance with cGMP, SAHPRA requirements, approved SOPs and product specifications.
• Monitor production activities, line clearance, material segregation, equipment verification and manufacturing conditions to maintain quality and regulatory compliance.
• Review batch manufacturing records, material reconciliations and production documentation for accuracy, completeness and data integrity.
• Draft, review, update and implement SOPs, work instructions, batch records and other GMP-controlled documentation.
• Investigate production deviations, non-conformances, OOS/OOT results and quality incidents, including root cause analysis and CAPA implementation.
• Support process validation, cleaning validation, equipment qualification, risk assessments and change control activities.
• Identify and implement continuous improvement initiatives to enhance manufacturing efficiency while maintaining product quality.
• Conduct GMP, SOP, manufacturing process and data integrity training, ensuring personnel competency and accurate training records.
• Support internal, customer and regulatory audits, including SAHPRA inspections, audit findings and corrective actions.
• Ensure production areas remain inspection-ready and compliant with occupational health, safety and environmental requirements.

Minimum Requirements

• Bachelor of Pharmacy (BPharm).
• Registration with the SAPC.
• 3-5 years' pharmaceutical manufacturing experience.
• Experience in solid dosage, liquids, creams or sterile manufacturing environments.
• Experience with GMP systems, regulatory inspections, SOP development and document control.
• Knowledge of SAHPRA regulations, PIC/S GMP guidelines and pharmaceutical manufacturing processes.
• Experience in batch documentation, deviation investigations, CAPA management, root cause analysis and process validation.
• Understanding of risk management, data integrity requirements and production quality standards.
• Strong leadership, problem-solving and decision-making capabilities.

The ideal candidate will be quality-driven, detail-oriented and committed to maintaining high pharmaceutical manufacturing standards. Strong analytical thinking, problem-solving, communication and decision-making skills are essential, together with ethical conduct, resilience, effective stakeholder engagement and a continuous improvement mindset.