Principal Statistical Programmer - SAS/R, Remote

Unifi Africa; Stellenbosch; Remote; ZAR 900,000 - 1,200,000; Full time

Job summary

Cytel Inc. is seeking a Senior/Principal Statistical Programmer (SAS + R) to be remote and work on sponsor-dedicated projects with a global pharma client, under Cytel's support.

You will lead programming activities, generate SDTM/ADaM, define.xml, support regulatory submissions, oversee CROs, ensure data quality, and contribute to standards.

Applicants should have 7+ years experience and strong communication; independent work style. This role offers remote work with international collaboration.

Qualifications

• Bachelor's degree in CS, data science, math, or statistics.
• 7+ years of statistical programming in biotech/pharma.
• Expert SAS programming and clinical programming processes.
• Extensive CDISC SDTM/ADaM/Define.xml experience.
• Experience supporting regulatory submissions with FDA/ICH.
• Ability to work independently.
• Excellent written and verbal communication and leadership.

Responsibilities

• Generate SDTM/ADaM specs, datasets, and define.xmls for multiple studies.
• Develop SAS programs for datasets, listings, tables, and graphs.
• Deliver high-quality programming outputs and validate scripts.
• Oversee CRO programmers to meet timelines.
• Support clinical study reports and regulatory submissions.
• Ensure compliance with FDA/ICH regulations and GCP.
• Contribute to standards, SOPs, and data validation plans.
• Collaborate with CROs, vendors, and clinical partners.

Skills

SAS programming

R programming

CDISC standards (SDTM/ADaM/Define.xml)

FDA/ICH regulatory submissions

Independent work / leadership

Communication skills

CRO oversight

Education

Bachelor's degree in Computer Science, Data Science, Mathematics, or Statistics

Tools

Python

Java

Shiny

Unix/Linux

Git

Markdown

Job description

Cytel Inc. is seeking a Senior/Principal Statistical Programmer (SAS + R) to be remote and work on sponsor-dedicated projects with a global pharma client, under Cytel's support.

You will lead programming activities, generate SDTM/ADaM, define.xml, support regulatory submissions, oversee CROs, ensure data quality, and contribute to standards.

Applicants should have 7+ years experience and strong communication; independent work style. This role offers remote work with international collaboration.