Principal Statistical Programmer - SAS + R (Remote)

Placements24; East London; Remote; ZAR 1,985,000 - 2,977,000; Full time

Job summary

At Cytel, the Senior/Principal Statistical Programmer will be embedded with a global pharmaceutical client, delivering SDTM/ADaM specifications, datasets, and complex listings with SAS and R.

You will lead CRO programming deliverables, ensure regulatory-compliant submissions, and contribute to standards and documentation across multiple studies, all while working with autonomy and strong communication.

Qualifications

• Bachelor's degree in computer science, data science, mathematics, or statistics.

Responsibilities

• Generate SDTM, ADaM specifications, datasets, reviewer's guide and define.xml files for multiple studies
• Develop SAS programs which generate datasets, complex listings, tables and graphs
• Deliver high-quality statistical programming results with SAS and/or R
• Oversee CRO programming deliverables to meet timelines
• Support preparation of clinical study reports, regulatory submissions, publications, DSURs, and exploratory analyses
• Follow FDA regulations and guidelines for electronic submissions
• Contribute to the creation and validation of standards for programming tools, outputs, and macros
• Develop CRFs, edit check specifications, and data validation plans
• Provide review/author data transfer specifications for external vendor data
• Collaborate with CROs, software vendors, and clinical partners to meet timelines
• Provide review/author SOPs and Work Instructions for statistical programming practices

Skills

SAS programming

CDISC SDTM/ADaM

Regulatory submissions

Leadership

Independent worker

Communication skills

R programming

Biostatistics collaboration

Education

Bachelor's degree in Computer Science / Data Science / Mathematics / Statistics

Tools

SAS

R

Python

Java

Shiny

Unix/Linux

Git

Define.xml

Job description

At Cytel, the Senior/Principal Statistical Programmer will be embedded with a global pharmaceutical client, delivering SDTM/ADaM specifications, datasets, and complex listings with SAS and R.

You will lead CRO programming deliverables, ensure regulatory-compliant submissions, and contribute to standards and documentation across multiple studies, all while working with autonomy and strong communication.