Pharmaceutical Research Scientist (Drug Discovery)

Placements24; Kempton Park; Presencial; ZAR 1.200.000 - 1.800.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Competitive salary

Health & wellness benefits

Retirement fund contributions

Descripción de la vacante

Placements24 is seeking a Pharmaceutical Research Scientist in Gauteng to lead drug discovery efforts at our client's state-of-the-art facility in Tembisa. The role requires a Ph.D.

or equivalent, a strong publication record, and extensive experience in target identification and assay development. The successful candidate will work in a multidisciplinary team, designing complex experiments, coordinating with chemists and toxicologists, and driving project milestones toward candidate selection.

Formación

• PhD in a life sciences field with strong publication record.
• 3–5 years of postdoctoral or industry drug-discovery experience.
• Proven expertise in cell-based assays, molecular biology techniques, and in vivo models.
• Strong understanding of drug development processes and regulatory considerations.
• Excellent data analysis and presentation skills, with relevant software knowledge.

Responsabilidades

• Design and execute complex biological experiments to identify and validate potential drug targets.
• Develop and optimize assays for screening compound libraries and evaluating drug candidate efficacy and safety.
• Conduct in vivo and in vitro studies to assess PK/PD properties of therapeutics.
• Analyze data, interpret results, and present findings at internal meetings and conferences.
• Collaborate with medicinal chemists, toxicologists, and clinical teams to advance candidates through development.
• Maintain detailed lab notebooks and prepare scientific reports and publications.
• Stay current with literature and technological advancements in drug discovery.

Conocimientos

Cell-based assay design

Molecular biology techniques

Data analysis (GraphPad Prism, R)

Educación

PhD in Pharmacology/Biochemistry/Molecular Biology

Herramientas

GraphPad Prism

R

Descripción del empleo

About the Role

Our client, a prominent player in the pharmaceutical industry, is looking for a dedicated and innovative Pharmaceutical Research Scientist to join their state-of-the-art facility in Tembisa, Gauteng. This role is central to the company's drug discovery efforts, focusing on identifying and validating novel therapeutic targets and developing innovative drug candidates. The successful candidate will work within a multidisciplinary team of scientists, contributing to cutting-edge research that aims to address unmet medical needs. This position requires a Ph.D. or equivalent advanced degree and a strong publication record in a relevant field. The opportunity is based at our client's cutting-edge research center, offering access to advanced technologies and a collaborative scientific environment in Tembisa, Gauteng. This is a key role for an individual passionate about advancing pharmaceutical science and making a tangible impact on patient health.

Key Responsibilities

• Design and execute complex biological and pharmacological experiments to identify and validate potential drug targets.
• Develop and optimize assays for screening compound libraries and evaluating drug candidate efficacy and safety.
• Conduct in vivo and in vitro studies to assess pharmacokinetic and pharmacodynamic properties of potential therapeutics.
• Analyze experimental data, interpret results, and present findings at internal project meetings and scientific conferences.
• Contribute to the development of research strategies and proposals, seeking new avenues for drug discovery.
• Collaborate closely with medicinal chemists, toxicologists, and clinical development teams to advance drug candidates through the development pipeline.
• Maintain detailed laboratory notebooks and prepare scientific reports and publications.
• Stay current with the latest scientific literature and technological advancements in drug discovery and relevant therapeutic areas.

Requirements

• Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a closely related life science discipline.
• Minimum of 3-5 years of postdoctoral or industry research experience in drug discovery.
• Proven expertise in designing and performing cell-based assays, molecular biology techniques, and relevant in vivo models.
• Strong understanding of drug development processes and regulatory considerations.
• Excellent data analysis and interpretation skills, with experience in relevant software (e.g., GraphPad Prism, R).
• Demonstrated ability to work independently and collaboratively within a fast-paced research environment.
• Strong communication and presentation skills, with a track record of scientific publications.
• Experience working in a laboratory setting in Tembisa, Gauteng.

Benefits

• Our client provides a competitive salary, comprehensive health and wellness benefits, retirement fund contributions, and generous paid time off.
• Opportunities for continuous learning, professional growth, and participation in international conferences are actively supported.
• Employees are part of an innovative and supportive research culture dedicated to scientific excellence in Tembisa, Gauteng.