Lead Computational Scientist

Placements24; Mbombela (Nelspruit); Hybrid; ZAR 1,600,000 - 2,200,000; Full time

Benefits offered by this job

Highly competitive salary

Bonus package

Equity potential

Medical, dental, vision insurance

Hybrid work environment

Job summary

Placements24 in Nelspruit is seeking a Lead Computational Scientist to guide an advanced research team in applying computational methods to drug discovery and development. You will lead a group, develop modeling tools, and collaborate with experimental teams to accelerate progress.

The role requires a PhD and 8+ years in computational science, with experience in leading scientific teams and expertise in molecular modeling, cheminformatics, structural biology, or systems biology.

Qualifications

• PhD in a quantitative field with substantial computational biology/chemistry experience.
• 8+ years in computational science, with drug discovery industry exposure.
• Proven leadership of scientific teams.
• Expertise in molecular modeling, cheminformatics, structural biology, or systems biology.
• Strong programming in Python, C++, or Fortran with relevant scientific packages.

Responsibilities

• Lead the computational science group with scientific direction and project management.
• Develop and implement advanced computational models, simulations, and data analysis for biological systems.
• Collaborate with experimental biologists, chemists, and pharmacologists to integrate computational findings.
• Design studies using molecular dynamics, structure-based design, and systems biology.
• Oversee development and maintenance of computational infrastructure and software tools.
• Present results to internal teams and external partners.

Skills

Leadership

Python

C++

Fortran

Molecular modeling

Cheminformatics

Systems biology

Education

PhD in Computational Chemistry/Computational Biology/Physics

Tools

Molecular modeling software

Cheminformatics tools

Structure-based design tools

Job description

About the Role

Our client is seeking an innovative and experienced Lead Computational Scientist to join their advanced research team in Nelspruit . This role is instrumental in applying computational methodologies to solve complex biological problems, particularly in areas of drug discovery and development. You will lead a team of computational scientists, oversee the development of sophisticated modeling and simulation tools, and collaborate closely with experimental teams to accelerate research progress. This hybrid position balances essential on-site collaboration in our modern facilities with the flexibility of remote work, fostering productivity and innovation.

Key Responsibilities

• Lead the computational science group, providing scientific direction, mentorship, and project management.


• Develop and implement advanced computational models, simulations, and data analysis strategies for biological systems.


• Collaborate closely with experimental biologists, chemists, and pharmacologists to integrate computational findings into research programs.


• Design and execute studies utilizing techniques such as molecular dynamics, structure-based drug design, and systems biology approaches.


• Oversee the development and maintenance of computational infrastructure and software tools.


• Present complex computational results and strategies to internal teams and external partners.

Requirements

• Ph.D. in Computational Chemistry, Computational Biology, Physics, or a related quantitative field.


• Minimum of 8 years of relevant experience in computational science, with a significant portion in drug discovery or a related industry.


• Proven experience in leading and managing scientific teams.


• Expertise in molecular modeling, cheminformatics, structural biology, and/or systems biology.


• Strong programming skills in languages such as Python, C++, or Fortran, and experience with relevant scientific software packages.

Benefits

• Highly competitive salary, bonus structure, and potential for equity.


• Comprehensive medical, dental, and vision insurance.


• Significant opportunities for career advancement and professional development in a growing field.


• Access to world-class computational resources and cutting-edge research projects in Nelspruit .


• A dynamic hybrid work environment that encourages collaboration and innovation.