Lead Bio-Process Engineer

Placements24; Durban; On-site; ZAR 1,400,000 - 1,900,000; Full time

Benefits offered by this job

Competitive remuneration

Medical, dental, vision insurance

Bonuses & stock options

Generous PTO

Professional development

Access to cutting-edge labs

Innovative work culture

Job summary

Placements24 seeks a Lead Bio-Process Engineer in Durban, South Africa, to drive design, optimization, and scale-up of bioprocesses for novel therapeutics. You will oversee cross-functional teams, ensure GMP-compliant operations, and lead process validation efforts.

The role demands a PhD/masters in a related field with 8+ years in bioprocess development and manufacturing, and strong leadership and problem-solving skills within a biotech or pharma setting.

Qualifications

• Master's or Ph.D. in Bio-process Engineering, Chemical Engineering, Biotechnology, or a related field.
• Minimum of 8 years of progressive experience in bioprocess development and manufacturing within the pharmaceutical/biotech industry.
• Proven track record in leading teams and managing complex bioprocess engineering projects.
• Strong knowledge of GMP regulations and validation principles.
• Experience with process modeling and simulation tools is a plus.

Responsibilities

• Lead design, development, and optimization of bioprocesses for biologics production (cell culture, fermentation, downstream processing).
• Oversee pilot-scale and commercial-scale manufacturing operations ensuring quality and regulatory compliance (GMP).
• Manage a team of bio-process engineers and technicians with mentorship and performance management.
• Develop and execute process validation strategies and campaigns.
• Prepare technical reports and regulatory documentation.
• Collaborate with R&D, QA, and manufacturing for seamless project execution.
• Identify and implement technologies to improve efficiency and reduce costs.

Skills

Team leadership

Problem solving

Decision making

Communication

Education

Master's or PhD in Bio-process/Chemical/Biotechnology

Job description

About the Role

Our client, a pioneering biotechnology firm, is seeking an accomplished Lead Bio-Process Engineer to spearhead their innovative research and development initiatives in Durban, KwaZulu-Natal . This senior role demands a visionary leader with extensive expertise in designing, optimizing, and scaling up bioprocesses for the development of novel therapeutic agents. You will be at the forefront of biotechnological advancement, managing complex projects from concept to production, ensuring efficiency, quality, and regulatory compliance. The successful candidate will possess a strong scientific background coupled with exceptional leadership and project management skills. This is an exceptional opportunity to make a significant impact in the rapidly growing biotech sector within Durban .

Key Responsibilities

• Lead the design, development, and optimization of bioprocesses for the production of biologics, including cell culture, fermentation, and downstream purification.
• Oversee pilot-scale and commercial-scale manufacturing operations, ensuring adherence to strict quality and regulatory standards (e.g., GMP).
• Manage a team of bio-process engineers and technicians, providing technical guidance, mentorship, and performance management.
• Develop and execute process validation strategies and campaigns.
• Troubleshoot and resolve complex technical issues related to bioprocess operations.
• Collaborate with R&D scientists, quality assurance, and manufacturing departments to ensure seamless project execution.
• Identify and implement innovative technologies and process improvements to enhance efficiency and reduce costs.
• Prepare technical reports, documentation, and presentations for internal stakeholders and regulatory agencies.
• Ensure all operations comply with safety and environmental regulations.

Requirements

• Master's or Ph.D. in Bio-process Engineering, Chemical Engineering, Biotechnology, or a related field.
• Minimum of 8 years of progressive experience in bioprocess development and manufacturing within the pharmaceutical or biotechnology industry.
• Proven track record in leading teams and managing complex bioprocess engineering projects.
• In-depth knowledge of mammalian cell culture, microbial fermentation, and downstream processing techniques.
• Strong understanding of GMP regulations and validation principles.
• Experience with process modeling and simulation tools is a plus.
• Excellent analytical, problem-solving, and decision-making skills.
• Exceptional communication, interpersonal, and leadership abilities.
• Familiarity with scale-up challenges and technology transfer processes.

Benefits

• Highly competitive remuneration package reflecting your expertise and leadership.
• Comprehensive medical, dental, and vision insurance plans.
• Performance-based bonuses and potential for stock options.
• Generous paid time off and holiday schedule.
• Professional development opportunities, including advanced training and conference participation.
• Access to cutting-edge laboratory facilities and advanced manufacturing technologies in Durban, KwaZulu-Natal.
• A dynamic and innovative work culture that fosters growth and collaboration.