Clinical Trial Manager - Oncology

Placements24; Centurion; On-site; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Health, dental, and vision insurance

Bonus structure

Retirement plan with company matching

Generous paid time off

Job summary

Placements24 is recruiting an accomplished Clinical Trial Manager specialized in Oncology to lead complex oncology trials in Centurion, Gauteng. You will oversee planning, execution, and close-out, ensuring compliance with ICH-GCP and regulatory requirements while mentoring CRAs and staff.

The role demands 5+ years in clinical trial management with a strong oncology focus, excellent communication, and proven site management skills. Based in Centurion with competitive compensation and benefits.

Qualifications

• Bachelor’s degree in life sciences required; advanced degree preferred.
• Extensive experience in oncology clinical research and trial management.
• Proven leadership, communication, and regulatory submission skills.

Responsibilities

• Oversee all phases of oncology trials from start-up to close-out.
• Develop and manage study budgets, timelines, and resources.
• Select, train, and manage sites and investigators.
• Oversee monitoring to ensure data integrity and patient safety.
• Ensure compliance with ICH-GCP, regulations, and study protocols.
• Prepare essential trial documents (IBs, protocols).
• Liaise with regulators and ethics committees.
• Troubleshoot issues during trial conduct.
• Mentor CRAs and staff.

Skills

Leadership

Project management

ICH-GCP

Regulatory submission

Multi-center trials

EDC systems

Education

Bachelor's degree in life science

Master's degree preferred

Tools

CTMS

EDC systems

Job description

About the Role

Our client, a leading Contract Research Organization (CRO) dedicated to advancing global health, is looking for an accomplished Clinical Trial Manager specializing in Oncology to join their team in Centurion, Gauteng . This critical role involves overseeing the planning, execution, and completion of complex oncology clinical trials, ensuring they are conducted in accordance with regulatory guidelines, protocols, and ethical standards. You will be responsible for managing all aspects of clinical trial operations, from site selection and initiation to data monitoring and close-out. The ideal candidate will possess extensive experience in oncology clinical research, strong leadership capabilities, and a thorough understanding of ICH-GCP guidelines. This is an exceptional opportunity to contribute to vital cancer research and treatment advancements within a supportive and growth-oriented organization. Your expertise will be key to delivering successful trial outcomes.

Key Responsibilities

• Manage all phases of oncology clinical trials, from study start-up to close-out.
• Develop and manage study budgets, timelines, and resources effectively.
• Select, train, and manage clinical trial sites and investigators.
• Oversee clinical monitoring activities to ensure data integrity and patient safety.
• Ensure compliance with ICH-GCP, regulatory requirements, and study protocols.
• Prepare and manage essential trial documentation, including investigator brochures and study protocols.
• Liaise with regulatory authorities, ethics committees, and other stakeholders.
• Troubleshoot and resolve issues that arise during trial conduct.
• Mentor and guide clinical research associates (CRAs) and other study staff.

Requirements

• Bachelor's degree in a life science, nursing, or related field; Master's degree or higher preferred.
• Minimum of 5 years of experience in clinical trial management, with a significant focus on oncology trials.
• In-depth knowledge of ICH-GCP, regulatory submission processes, and clinical trial methodology.
• Proven experience in managing multi-center international clinical trials.
• Strong leadership, project management, and organizational skills.
• Excellent communication, negotiation, and interpersonal skills.
• Proficiency in clinical trial management software and electronic data capture (EDC) systems.
• Ability to work effectively in a demanding, fast-paced environment in Centurion, Gauteng .

Benefits

Our client offers a highly competitive salary package, reflecting the seniority and responsibilities of this role. Benefits include comprehensive health, dental, and vision insurance, a substantial annual bonus structure, a retirement savings plan with company matching, and generous paid time off. We also provide extensive opportunities for professional development, including advanced training courses and conference attendance. This role is based at our offices in Centurion, Gauteng , offering a collaborative work environment and the chance to significantly impact cancer patient care.