Clinical Research Associate II - Pharmaceutical Trials

Placements24; South Africa; On-site; ZAR 600,000 - 900,000; Full time

Benefits offered by this job

Health insurance

Company vehicle

Travel allowance

Professional development

Retirement plan

Job summary

Placements24 is seeking a Clinical Research Associate II to oversee and manage clinical trials from our office in Tembisa, Gauteng, with regular site visits. You will ensure protocol adherence, GCP compliance and data integrity while liaising with investigators and site staff.

The role requires 3–5 years of CRA experience, knowledge of ICH-GCP, and experience with EDC systems. Travel to trial sites is required; great organizational and communication skills are essential.

Qualifications

• Bachelor’s degree in Life Sciences, Nursing, Pharmacy or related field; Master’s preferred.
• 3–5 years’ experience as a Clinical Research Associate with site monitoring.
• Solid knowledge of ICH-GCP and regulatory requirements; proficient in EDC.

Responsibilities

• Monitor trial sites for protocol, SOP, GCP, and regulatory compliance.
• Verify accuracy and completeness of data at study sites.
• Perform SDV and review CRFs.
• Conduct site initiation, interim monitoring, and close-out visits.
• Manage site relationships and provide ongoing support to investigators.
• Resolve data queries and site issues promptly.
• Oversee investigational product management at sites.
• Prepare and present monitoring reports.
• Participate in site personnel training and documentation

Skills

Site monitoring

Data integrity

Analytical thinking

Time management

Communication skills

Education

Bachelor’s degree in Life Sciences/Nursing/Pharmacy

Master’s degree (plus)

Tools

EDC systems

Job description

About the Role

Our client, a prominent name in the pharmaceutical industry, is actively seeking a dedicated Clinical Research Associate II (CRA II) to join their expanding clinical operations team. This crucial role involves overseeing and managing clinical trials, ensuring adherence to study protocols, Good Clinical Practice (GCP) guidelines, and regulatory requirements. The position is primarily office-based, located in Tembisa, Gauteng , with regular site visits required. The successful candidate will play a vital part in the successful execution of clinical studies, contributing to the development of life‑saving medications. This role demands a high level of organizational skill, meticulous attention to detail, and strong interpersonal abilities to liaise effectively with investigators, site staff, and internal project teams. If you are passionate about clinical research and eager to contribute to meaningful pharmaceutical advancements, this opportunity is for you. The non‑remote nature ensures full immersion in the operational aspects of trial management.

Key Responsibilities

• Monitor clinical trial sites to ensure compliance with protocols, SOPs, GCP, and applicable regulations.
• Verify the accuracy, completeness, and integrity of clinical data collected at study sites.
• Perform source data verification (SDV) and review case report forms (CRFs).
• Conduct site initiation, interim monitoring, and close‑out visits.
• Manage site relationships and provide ongoing support to investigators and study coordinators.
• Ensure timely resolution of data queries and site issues.
• Oversee the drug accountability and investigational product management at sites.
• Prepare and present site monitoring reports.
• Participate in the training of site personnel.
• Contribute to the development of clinical trial documentation.

Requirements

• Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related field; a Master's degree is a plus.
• Minimum of 3-5 years of experience as a Clinical Research Associate, with demonstrated experience in site monitoring.
• In‑depth knowledge of ICH‑GCP guidelines and regulatory requirements for clinical trials.
• Experience with electronic data capture (EDC) systems.
• Excellent organizational and time management skills.
• Strong analytical and problem‑solving abilities.
• Proficiency in written and verbal communication in English.
• Ability to travel to clinical trial sites as required.
• Detail‑oriented with a commitment to data accuracy and patient safety.
• Previous experience in the Tembisa, Gauteng area or surrounding regions is advantageous.

Benefits

• Competitive annual salary of ZAR .
• Performance‑based bonuses.
• Company‑provided vehicle or travel allowance for site visits.
• Comprehensive health insurance coverage.
• Retirement savings plan.
• Opportunities for professional development and advanced training in clinical research.
• Exposure to diverse therapeutic areas and innovative trial designs.
• Supportive team environment focused on collaboration and success in Tembisa, Gauteng .