Analytical Development Scientist - Pharmaceutical Analysis

Placements24; Klerksdorp; Hybrid; ZAR 600,000 - 980,000; Full time

Benefits offered by this job

Medical aid

Provident fund

Professional development

Job summary

Placements24 is seeking an Analytical Development Scientist for a state-of-the-art facility in Klerksdorp, North West. You will develop, validate, and implement analytical methods for pharmaceutical products, ensuring quality and regulatory compliance.

The role requires a strong analytical chemistry background, 4+ years in method development/validation, and hands-on experience with HPLC/UPLC/GC and spectroscopy. Collaboration with cross-functional teams is essential.

Qualifications

• Master's or Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, or related discipline.
• Minimum of 4 years of experience in analytical method development and validation.
• Hands-on experience with chromatographic techniques (HPLC, UPLC, GC) and spectroscopic methods.
• Strong understanding of QbD principles and validation strategies.
• Familiarity with regulatory expectations (SAHPRA, FDA, EMA).
• Excellent analytical, problem-solving, and critical thinking skills.
• Proficiency in data analysis software and statistics.
• Strong written and verbal communication skills.

Responsibilities

• Develop and validate new analytical methods for testing materials and finished products.
• Optimize existing methods to improve efficiency, robustness, and sensitivity.
• Perform method transfer activities to Quality Control laboratories.
• Characterize drug substances and products using chromatography and spectroscopy.
• Investigate and resolve analytical issues during development or routine testing.
• Prepare method validation reports for regulatory submissions.
• Stay current with literature and regulatory guidelines (ICH).
• Collaborate with cross-functional teams including formulation, manufacturing, and regulatory affairs.
• Maintain laboratory equipment and ensure GLP compliance.

Skills

Analytical thinking

Strong communication

Team collaboration

Problem solving

Education

Master's in Analytical Chemistry

PhD in Analytical Chemistry/Pharmaceutical Sciences

Tools

HPLC

UPLC

GC

UV-Vis

IR

Mass Spectrometry

Job description

About the Role Our client, a leading pharmaceutical organization, is actively seeking an Analytical Development Scientist to join their state-of-the-art facility in Klerksdorp, North West. This role is crucial for the development, validation, and implementation of robust analytical methods required for the characterization and quality control of pharmaceutical products. The ideal candidate will possess a strong scientific background in analytical chemistry and a passion for ensuring product integrity and safety. This position offers a significant opportunity to advance your career within the pharmaceutical industry in North West and contribute to the development of life-saving medicines.

Key Responsibilities

• Develop and validate new analytical methods for the testing of raw materials, intermediates, and finished pharmaceutical products.
• Optimize existing analytical methods to improve efficiency, robustness, and sensitivity.
• Perform method transfer activities to Quality Control laboratories.
• Characterize drug substances and drug products using a range of analytical techniques, including chromatography (HPLC, GC), spectroscopy (UV-Vis, IR, Mass Spec), and dissolution testing.
• Investigate and resolve analytical issues encountered during method development or routine testing.
• Prepare comprehensive method validation reports and documentation suitable for regulatory submissions.
• Stay current with scientific literature, emerging analytical technologies, and regulatory guidelines (e.g., ICH).
• Collaborate with cross-functional teams, including formulation, manufacturing, and regulatory affairs.
• Maintain laboratory equipment and ensure compliance with Good Laboratory Practices (GLP).

Requirements

• Master's or Ph.D. in Analytical Chemistry, Pharmaceutical Sciences, or a related discipline.
• Minimum of 4 years of experience in analytical method development and validation within the pharmaceutical industry.
• Extensive hands-on experience with chromatographic techniques (HPLC, UPLC, GC) and spectroscopic methods.
• Strong understanding of quality by design (QbD) principles and validation strategies.
• Familiarity with regulatory expectations for analytical development (e.g., SAHPRA, FDA, EMA).
• Excellent analytical, problem-solving, and critical thinking skills.
• Proficiency in data analysis software and statistical methods.
• Strong written and verbal communication skills, with the ability to document scientific work clearly and concisely.
• Ability to work independently and collaboratively in a team environment.

Benefits

Our client offers a competitive salary and benefits package, including medical aid, provident fund, and professional development opportunities. They foster a culture of scientific excellence and innovation. This role in Klerksdorp provides a stimulating career path in analytical science within the North West province, contributing to the critical area of pharmaceutical quality assurance.