USA-Data Scientist II (Clinical)

Mindlance; Waltham (MA); On-site; USD 80,000 - 110,000; Full time

Job summary

An established industry player is looking for a skilled Bioinformatics Contractor to join their Genomic Medicine Unit. In this role, you will leverage your expertise in bioinformatics and computational biology to support complex projects and collaborate with interdisciplinary teams. Your responsibilities will include building and executing bioinformatic pipelines, analyzing Next-Generation Sequencing data, and utilizing machine learning techniques to identify potential biomarkers. This full-time position offers a unique opportunity to contribute to groundbreaking research in a dynamic, on-site environment.

Qualifications

• 3+ years of experience in bioinformatics or computational biology.
• Advanced degree (MS or PhD) in Bioinformatics or related field.

Responsibilities

• Build and execute bioinformatic pipelines for various NGS data types.
• Collaborate with cross-functional teams to support research initiatives.

Skills

Bioinformatics

Computational Biology

R Programming

Python Programming

Next-Generation Sequencing (NGS)

Data Visualization

Machine Learning

Biostatistics

Interpersonal Skills

Education

Master's Degree in Bioinformatics

PhD in Computational Biology

Tools

Nextflow

Snakemake

HPC

AWS S3

GCP

Git

Job description

Bioinformatics/Computational Biology Scientist
Job Overview
We are seeking an expert Bioinformatics Contractor with 3+ years of research experience to support Genomic Medicine Unit (GMU) programs and platform work. The ideal candidate will have deep expertise in various bioinformatic data analyses and computing infrastructure and be able to work independently on complex projects within interdisciplinary team.
This position is 1 year contract with possibility of extension. Full time, on site at Waltham, MA.
Required Qualifications
• 3+ years of experience in bioinformatics or computational biology
• Advanced degree (MS or PhD) in Bioinformatics, Computational Biology, or related field
• Demonstrated expertise in the following areas:
• Developing and running pipelines for Next-Generation Sequencing (NGS) analysis including:
• Bulk RNA sequencing (DEG, WGCNA, etc)
• Single-cell/nuclei RNA sequencing
• Amplicon sequencing
• Endogenous miRNA profiling, off-target analysis, artificial miRNA design
• Biomarker analyses based on proteomic, transcriptomic data
• Long-read sequencing (PacBio, Oxford Nanopore)
• Querying and curation of publicly available omic datasets
• Effective data visualization
• Strong interpersonal skills
Responsibilities
• Build and execute bioinformatic pipelines
• Analyze various NGS data types (bulk, single-cell, amplicon, long read)
• Manage data and workflows
• Interface with internal teams of scientists and external partners
• Design artificial miRNAs with minimal off-target effects and analyze supporting data
• Use machine learning, biostatistical analyses, WGCNA, pathways analysis to identify potential biomarkers from complex datasets
• Analyze long-read sequencing data for vector quality control
• Query, curate, and analyze publicly available omic datasets relevant to research objectives
• Collaborate with cross-functional teams to support research initiatives
• Participate in experimental design
• Document analyses and present findings to stakeholders
Technical Skills
• Proficiency in R, Python
• Expertise with NGS data analysis
• Expertise in building pipelines, automating workflows (Nextflow, snakemake)
• Expertise using HPC, AWS s3, GCP, git
• Familiarity with public genomic and other databases and data repositories (GTEx, SRA, UKBB)

EEO:

“Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of – Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.”