US Oncology Medical Lead, Lung

AstraZeneca plc; Gaithersburg (MD); On-site; USD 193,000 - 290,000; Full time

Benefits offered by this job

401(k) plan

Paid vacation and holidays

Health benefits

Equity-based incentives

Job summary

AstraZeneca plc seeks a US Oncology Medical Lead for Lung to set direction and drive evidence generation that informs clinical practice across the US. You will lead cross-functional execution from early development through launch, partnering with clinical experts, advocacy groups, and internal teams to improve patient outcomes.

You will guide site engagement, plan publications, and ensure governance and compliance while building a high-performing Medical Affairs team nationwide.

Qualifications

• Advanced degree in science with broad Medical Affairs exposure.
• Experience driving medical strategy alignment with corporate goals.
• Proven ability to manage stakeholder relationships with payers, providers and patients.
• Strong understanding of evidence generation, trials, and real-world data.

Responsibilities

• Own US medical strategy for lung cancer portfolio and align with corporate objectives.
• Define high-value evidence gaps; plan interventional and real-world studies.
• Lead launch readiness and lifecycle activities for new indications.
• Collaborate with Market Access, HEOR, Compliance, Sales, and Marketing.

Skills

Medical leadership

Stakeholder engagement

Evidence generation

Clinical trial knowledge

Cross-functional collaboration

Education

Master’s degree in scientific discipline

Bachelor’s degree with MA experience considered

Job description

Are you ready to lead the US medical strategy that shapes the future of lung cancer care and meaningfully improves patient outcomes? In this role based in Gaithersburg, you will connect cutting-edge science with real-world practice — translating evidence into decisions that help physicians treat people living with lung cancer and support the families and caregivers around them.

As the US Oncology Medical Lead for Lung, you will set direction, guide evidence generation, and elevate cross-functional execution from early development through launch and beyond. You will champion partnerships with clinical experts, advocacy groups, and internal teams to change how lung cancer is treated across the country.

Accountabilities

• Strategic Medical Leadership: Own the US medical strategy for the lung cancer portfolio, aligning plans to corporate objectives and unmet patient needs, and communicating clear priorities that drive measurable impact.
• Evidence Strategy and Generation: Define high-value evidence gaps; design and deliver interventional, non-interventional, and real-world evidence initiatives; translate insights into plans that inform clinical practice, access, and lifecycle decisions.
• Launch and Lifecycle Excellence: Lead medical launch readiness for new indications and combinations; optimize post-launch activities to shift standards of care and sustain clinical relevance.
• Cross-Functional Partnership: Integrate medical perspectives across Market Access, HEOR, Compliance, Sales, and Marketing; influence operational plans with clear scientific rationale and data‑driven recommendations.
• Clinical Trial Support: Guide site and investigator engagement, feasibility inputs, and enrollment acceleration; support data interpretation to ensure timely, high-quality study delivery and impactful readouts.
• External Engagement and Thought Leadership: Build trusted partnerships with scientific experts, professional societies, and patient advocacy organizations; represent Medical Affairs at congresses, advisory boards, and external forums.
• Scientific Communications and Education: Direct publication strategies, medical messaging, and congress plans; deliver concise education and training that elevate field medical and commercial capabilities.
• Governance and Compliance: Review and approve protocols, study proposals, and publications; ensure rigorous adherence to internal governance, ethical standards, and regulatory requirements.
• Patient-Centric Insights: Systematically capture and integrate patient and caregiver perspectives to inform strategies, materials, and clinical development plans that reflect real-world needs.
• People Leadership and Capability Building: Develop, mentor, and empower team members; cultivate an inclusive, high-performance culture and scalable Medical Affairs capabilities that deliver sustained value.
• Business Acumen and Resource Stewardship: Manage budgets, vendors, and metrics; prioritize activities that demonstrate medical value and efficient use of resources.

Essential Skills/Experience

• Master’s degree in a scientific discipline
• Bachelor’s degree with extensive Medical Affairs experience considered
• Significant experience in Medical Affairs within the pharmaceutical industry
• Demonstrated project and relationship management skills, including stakeholder engagement (payers, providers, and patients)
• Experience with evidence generation and clinical trial methodology
• Strong foundation in business acumen and financial management
• Expertise in working within matrix team environments

Desirable Skills/Experience

• Advanced scientific or medical degree (e.g., PhD, PharmD, MD)
• Understanding of the latest developments in technical, regulatory, policy, and real-world evidence generation

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca

Here, science meets strategy to change the practice of medicine. You will work with brave thinkers across disciplines to create and communicate evidence that directly informs how cancer is treated in clinics every day. We value kindness alongside ambition, pairing openness and transparency with the drive to move faster for patients. With access to a deep pipeline, real-world data expertise, and partners who turn insights into action, your contribution will scale—from elevating US lung cancer care to advancing progress across oncology and beyond.

The annual base pay for this position ranges from $ 193,281 – 289,922 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job‑related knowledge, skills, and experience. In addition, our positions offer a short‑term incentive bonus opportunity; eligibility to participate in our equity‑based long‑term incentive program. Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at‑will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.