US Market Access Director — Early Asset Value Strategy

AstraZeneca GmbH; Wilmington (DE); Hybrid; USD 180,000 - 235,000; Full time

Job summary

AstraZeneca in Wilmington, DE seeks a SrDirector, US Medical Early Asset - Market Access to lead US access strategy for early assets. You will shape payer-focused value narratives, influence cross-functional teams, and ensure pricing, policy, and evidence considerations drive asset development from late discovery through Phase 2.

The role requires deep US payer knowledge, experience in HEOR, pricing, and cross-functional leadership across Clinical, Medical, Regulatory and Finance teams.

Qualifications

• Broad understanding of US payer and health-system environment.
• Strong HEOR, economic modeling, and value proposition development.

Responsibilities

• Define US payer-relevant elements of the Target Product Profile and shape differentiation claims.
• Provide US access input to clinical and RWE plans to support label, guidelines and payer coverage.
• Lead early value story development, core claims, and AMCP dossier requirements.
• Develop US pricing hypotheses, budget impact boundaries, and contracting scenarios.
• Co-create early economic models and RWE plans to support access and inform trial design.
• Assess policy landscape and channel dynamics impacting design and launch.
• Synthesize payer/IDN input and rapid tests to mitigate access hurdles.

Skills

Market access

HEOR

Pricing strategy

Stakeholder influence

Cross-functional leadership

Evidence strategy

Education

Bachelor's degree

Advanced degree

Job description

AstraZeneca in Wilmington, DE seeks a SrDirector, US Medical Early Asset - Market Access to lead US access strategy for early assets. You will shape payer-focused value narratives, influence cross-functional teams, and ensure pricing, policy, and evidence considerations drive asset development from late discovery through Phase 2.

The role requires deep US payer knowledge, experience in HEOR, pricing, and cross-functional leadership across Clinical, Medical, Regulatory and Finance teams.