Upstream Cell Culture Process Development Associate I/II

KBI Biopharma; Durham (NC); On-site; USD 50,000 - 70,000; Full time

Job summary

KBI Biopharma seeks an Upstream Cell Culture Process Development Associate to lead and assist cell culture and harvest projects for CHO cell lines in support of process development, scale-up, and technology transfer to cGMP manufacturing.

Responsibilities include set-up and operation of bioreactors from shake flasks to 200 L, data entry, and analysis of growth and productivity. The role requires a BS/MS with 1–3+ years in chemical engineering or biotechnology and strong MS Office skills.

Qualifications

• Bachelors plus 1–3+ years in Chemical Engineering, Biotechnology or related area.
• Working knowledge of mammalian cell culture.
• Advanced ability with Microsoft Office (Excel, PowerPoint and Word).
• Demonstrates ability to work both independently and as a member of a team.
• Flexibility to support cell culture processes over weekends and holidays (premium pay).

Responsibilities

• Assist set-up, operation, and analysis of cell culture and bioreactor processes including preparation, inoculation, sampling, feeding, data entry and data analysis forshake flasks and various scale bioreactors.
• Lead in maintaining experiments and perform calculations for growth rate and productivity.
• Perform data entry, plotting, and support writing of technical reports using MS Office.
• Maintain batch sheets and data binders following GDP.
• Assist in data analysis using DOE (Design Expert) and JMP and help write technical documents.
• Maintain a cell culture project plan including raw materials and equipment availability for lab and pilot-scale runs.
• Participate in process development teams and coach junior staff on cell culture techniques.

Skills

Mammalian cell culture

MS Office proficiency

Independent and team work

Customer service

Weekend/holiday flexibility

Education

Bachelor’s degree in Chemical Engineering or Biotechnology

Master’s degree in Chemical Engineering or Biotechnology

Tools

Design Expert (DOE)

JMP

MS Office (Excel, PowerPoint, Word)

Job description

KBI Biopharma seeks an Upstream Cell Culture Process Development Associate to lead and assist cell culture and harvest projects for CHO cell lines in support of process development, scale-up, and technology transfer to cGMP manufacturing.

Responsibilities include set-up and operation of bioreactors from shake flasks to 200 L, data entry, and analysis of growth and productivity. The role requires a BS/MS with 1–3+ years in chemical engineering or biotechnology and strong MS Office skills.