Upstream Bioprocess Research Associate

Krystal Biotech; Pittsburgh (Allegheny County); On-site; USD 65,000 - 90,000; Full time

Job summary

Krystal Biotech is seeking a highly motivated Research Associate to support Upstream Process Development for viral vector production. The role involves hands-on work with bench-scale bioreactors, mammalian cell culture, and process optimization to enable scale-up and tech transfer to manufacturing.

You will collaborate with cross-functional teams, design experiments, record data in electronic lab notebooks, and help troubleshoot equipment and workflows in a fast-paced, quality-focused

Qualifications

• Bachelor’s Degree in Biomedical Engineering, Chemical Engineering, Bioengineering or a related scientific discipline.
• Some understanding in aseptic technique, mammalian cell culture, bioreactor technology, cell biology, and/or virology.
• Familiarity with bioreactor operation and upstream processing is a plus.
• Familiarity with lab automation or basic coding is a plus.
• High capability of multitasking in a fast-paced team-oriented environment.
• Excellent oral and written communication skills.

Responsibilities

• Set up and operate bench scale bioreactors under the guidance of senior staff
• Perform mammalian cell culture using aseptic techniques
• Prepare buffers and media, maintain equipment, and order supplies to ensure the lab runs smoothly
• Provide technical support in the lab through equipment maintenance and troubleshooting
• Participate in study design and process development brainstorming sessions
• Design scientifically sound experiments and record data accurately in electronic lab notebooks
• Adhere to safety guidelines and maintain a clean and orderly lab environment
• Analyze experimental data and effectively communicate findings with manager and rest of process development team
• Interact with cross-functional teams (manufacturing, MSAT, etc.) to identify and solve problems encountered during process scale-up

Skills

Aseptic technique

Mammalian cell culture

Bioreactor technology

Cell biology

Virology

Lab automation / coding

Education

Bachelor’s degree in Biomedical Engineering, Chemical Engineering, Bioengineering or related field

Tools

Electronic lab notebooks

Job description

Krystal Biotech is seeking a highly motivated Research Associate to support Upstream Process Development for viral vector production. The role involves hands-on work with bench-scale bioreactors, mammalian cell culture, and process optimization to enable scale-up and tech transfer to manufacturing.

You will collaborate with cross-functional teams, design experiments, record data in electronic lab notebooks, and help troubleshoot equipment and workflows in a fast-paced, quality-focused