Upstream Bioprocess & QC Associate (Weekend PT)

SIGNOBIO INC; Houston (TX); On-site; USD 41,000 - 69,000; Part time

Benefits offered by this job

Onsite parking

Onsite gym

Career growth opportunities

Team-oriented culture

Job summary

Sino Biological’s Houston-based C4B facility is hiring an Upstream Associate to support recombinant protein and antibody expression using mammalian cell cultures, while contributing to quality control and analytical testing. The role emphasizes precise data handling, aseptic techniques, and teamwork across project scientists.

This entry-level position offers weekend work and potential for full-time hire, with exposure to HEK293/CHO workflows, lab maintenance, and cross-functional collaboration

Qualifications

• Bachelor’s degree in Biology, Cell Biology, Biochemistry, Biotechnology, or a related field.
• Lab experience with mammalian cell culture; HEK293 and CHO required.
• Familiarity with suspension culture and aseptic techniques.
• Basic experience with analytical assays such as SDS-PAGE, HPLC-SEC, UV-Vis, or endotoxin testing is a plus.
• Strong attention to detail, documentation, and troubleshooting skills.
• Flexible and adaptable to varying schedules or project demands.
• Effective communication skills and the ability to work collaboratively in a team-oriented environment.

Responsibilities

• Perform recombinant protein expression using mammalian systems such as HEK293 and CHO.
• Execute upstream workflows including cell thawing, expansion, transfection, and harvesting.
• Maintain lab cleanliness, including biosafety cabinets, incubators, and shared spaces.
• Handle and maintain cell cultures using proper aseptic techniques.
• Conduct protein quality control assays, including SDS-PAGE, HPLC-SEC, endotoxin testing, and UV-Vis measurements.
• Record data and observations in electronic lab notebooks accurately and promptly.
• Assist with media/reagent preparation, equipment setup, and maintenance tasks.
• Support instrument calibration, troubleshooting, and lab upkeep.
• Collaborate with downstream and cross-functional teams to ensure smooth project execution.
• Conduct product aliquoting to meet delivery timelines.
• Adhere to all safety and PPE protocols under federal, state, and local regulations.

Skills

Attention to detail

Documentation

Teamwork

Troubleshooting

Education

Bachelor’s degree in Biology or related

Tools

HEK293

CHO

SDS-PAGE

HPLC-SEC

UV-Vis

Job description

Sino Biological’s Houston-based C4B facility is hiring an Upstream Associate to support recombinant protein and antibody expression using mammalian cell cultures, while contributing to quality control and analytical testing. The role emphasizes precise data handling, aseptic techniques, and teamwork across project scientists.

This entry-level position offers weekend work and potential for full-time hire, with exposure to HEK293/CHO workflows, lab maintenance, and cross-functional collaboration