UNIV - Staff Scientist II - Department of Pharmacology

Medical University of South Carolina; Charleston (SC); On-site; USD 50,000 - 80,000; Full time

Job summary

An established industry player is seeking highly motivated individuals for postdoctoral positions in neuroimmunology. This exciting opportunity involves engaging in groundbreaking research on neuroinflammatory mechanisms and traumatic brain injury. You will work with advanced microscopy and various mouse models to explore the complexities of neuroimmune responses. Join a dynamic team that is at the forefront of developing novel therapeutic approaches and contribute to impactful research that could change the landscape of neurodegenerative disease treatment. If you are passionate about science and eager to make a difference, this role is for you.

Qualifications

• PhD or equivalent in biology or related field required.
• At least four years of experience in a research laboratory.

Responsibilities

• Participate in experimental procedures and data analysis.
• Collaborate with lab personnel and maintain records.

Skills

Neuroimmunology

Microsurgery

Data Analysis

Histology

Behavioral Assessment

Education

PhD in Biology or related field

Tools

Image Analysis Software

Advanced Microscopy

Job description

Job Description Summary

Seeking highly motivated individuals for postdoctoral positions in neuroimmunology for projects that encompasses basic and translational research.



Work in the laboratory is centered around the complement system and neuroinflammatory mechanisms. Ongoing projects involve investigating acute and chronic neuroimmune responses occurring after stroke or after different types of traumatic brain injury, including the long-term neurodegenerative sequalae of injury. For example, one project is focused on traumatic brain injury as a risk factor for Alzheimer’s Disease. Another project investigates pathogenic mechanisms of postnatal hemorrhagic stroke and neurodevelopmental consequences. Studies utilize various mouse models, and the laboratory is also developing several novel transgenic animals for these studies. Techniques currently utilized include advanced microscopy, cellular and molecular immune profile analysis, high dimensional analyses, and detailed assessments of motor and cognitive functions. The laboratory is also involved in the development (and commercialization) of novel therapeutic approaches, and has been a leader in the development of novel targeted complement inhibitory strategies.

Entity

Medical University of South Carolina (MUSC - Univ)

Worker Type

Employee

Worker Sub-Type

Research Grant

Cost Center

CC001032 COM PHARM Administration CC

Pay Rate Type

Salary

Pay Grade

University-00

Pay Range

0.00 - 0.00 - 0.000

Scheduled Weekly Hours

40

Work Shift

Job Description

Job summary

Seeking highly motivated individuals for postdoctoral positions in neuroimmunology for projects that encompasses basic and translational research.

Work in the laboratory is centered around the complement system and neuroinflammatory mechanisms. Ongoing projects involve investigating acute and chronic neuroimmune responses occurring after stroke or after different types of traumatic brain injury, including the long-term neurodegenerative sequalae of injury. For example, one project is focused on traumatic brain injury as a risk factor for Alzheimer’s Disease. Another project investigates pathogenic mechanisms of postnatal hemorrhagic stroke and neurodevelopmental consequences. Studies utilize various mouse models, and the laboratory is also developing several novel transgenic animals for these studies. Techniques currently utilized include advanced microscopy, cellular and molecular immune profile analysis, high dimensional analyses, and detailed assessments of motor and cognitive functions. The laboratory is also involved in the development (and commercialization) of novel therapeutic approaches, and has been a leader in the development of novel targeted complement inhibitory strategies.

Duties/Responsibilities

Participate in a project related to above described work, perform experimental procedures, including microsurgical procedures that include mouse models of stroke (ischemic and hemorrhagic) and traumatic brain injury. Prepare sections from mouse brains and process for histology and immune-microscopy. Perform various microscopy techniques. Evaluate mice via various behavioral tasks. 35%

In terms of the above listed techniques, analyze and interpret data. Will also involve use of image analysis software and generation of computer images. Determine behavioral outcomes in terms of pathophysiological findings. 35%

Collaborate with other lab personnel in related projects. Participate in lab meetings and project-specific meetings with other lab personnel. 15%

Keep records and up to date lab notebook/lab archives. Assist with writing manuscripts and grants. Keep up to date with relevant literature. 15%

Minimum Experience and Training Requirements: A PhD or equivalent in biology or other natural, life or health care science related to the assigned area of research. At least four years experience working in a research laboratory, and two years experience working in a related field to studies described above.

For further information or to apply (CV and names of 3 referees), please contact Dr. Stephen Tomlinson: [e-mail]

MUSC Minimum Training and Experience:

A Ph.D., M.D. or equivalent with two years postdoctorate experience plus evidence of scholarly activity as demonstrated by at least five first author publications.

MUSC Physical Requirements:

(Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift)

Ability to perform job functions in an upright position. (Continuous)
Ability to perform job functions in a seated position. (Continuous)
Ability to perform job functions while walking/mobile. (Frequent)
Ability to climb stairs. (Infrequent)
Ability to work indoors. (Continuous)
Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent)
Ability to bend at the waist. (Frequent)
Ability to twist at the waist. (Frequent)
Ability to perform 'pinching' operations. (Continuous)
Ability to fully use both hands/arms. (Continuous)
Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous)
Ability to fully use both legs. (Continuous)
Ability to reach in all directions. (Continuous)
Possess good finger dexterity. (Continuous)
Ability to maintain tactile sensory functions. (Continuous)
Ability to maintain good olfactory sensory function. (Continuous)
Ability to lift and carry 30 lbs., unassisted. (Frequent)
Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent)
Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent)
Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent)
Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent)
Ability to maintain 20/40 vision, corrected. (Continuous)
Ability to see and recognize objects close at hand. (Continuous)
Ability to see and recognize objects at a distance. (Continuous)
Ability to match or discriminate between colors. (Continuous)
Ability to determine distance/relationship between objects; depth perception. (Continuous)
Good peripheral vision capabilities. (Continuous)
Ability to maintain hearing acuity, with correction. (Continuous)
Must be ambidextrous.
Ability to perform gross motor functions with frequent fine motor movements. (Continuous)
Ability to be qualified physically (by medical personnel) for respirator use, initially and annually.
Ability to work alone in isolated areas, such as darkrooms. (Frequent)

Additional New Requirements:
Ability to obtain and maintain a valid drivers license.
Computer literacy.
Ability to work rotating shifts as required.
Ability to work overtime as required.
Ability to learn and use new processes, tools and equipment as required.

Additional Job Description

Physical Requirements: (Note: The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors. (Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform 'pinching' operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions. (Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 30 lbs., unassisted. (Frequent) Ability to lift objects, up to 30 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 30 lbs., from height of 72 inches to floor level, unassisted. (Frequent) Ability to push/pull objects, up to 50 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 30 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability to maintain 20/40 vision, corrected. (Continuous) Ability to see and recognize objects close at hand. (Continuous) Ability to see and recognize objects at a distance. (Continuous) Ability to match or discriminate between colors. (Continuous) Ability to determine distance/relationship between objects; depth perception. (Continuous) Good peripheral vision capabilities. (Continuous) Ability to maintain hearing acuity, with correction. (Continuous) Ability to perform gross motor functions with frequent fine motor movements. (Continuous) Ability to be qualified physically (by medical personnel) for respirator use, initially and annually. Ability to work alone in isolated areas, such as darkrooms. (Frequent) Additional New Requirements: Ability to obtain and maintain a valid drivers license. Computer literacy. Ability to work rotating shifts as required. Ability to work overtime as required. Ability to learn and use new processes, tools and equipment as required.

If you like working with energetic enthusiastic individuals, you will enjoy your career with us!

The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.

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