Translational Genomics Scientist (Multi-Omics & HPC)

Boston Children's Hospital; Boston (MA); On-site; USD 110,000 - 160,000; Full time

Job summary

Boston Children's Hospital is seeking a Genomic Scientist to lead integrative analyses of RNA sequencing, methylation, long-read sequencing, and WGS/WES data in a translational pediatric context.

You will develop pipelines, apply variant interpretation algorithms, and collaborate with physician-scientists to turn clinical requirements into computational solutions, contributing to research and clinical care.

Qualifications

• PhD in Genetics, Genomics, Computational Biology or related field preferred.
• Strong programming in Python, R, and Bash under Linux/HPC.
• Experience analyzing WGS/WES, RNA-seq, methylation, or long-read data.
• Familiarity with ACMG guidelines and clinical NGS frameworks.

Responsibilities

• Lead integrative bioinformatic analyses of multi-omics data.
• Develop and maintain reproducible pipelines and variant interpretation workflows.
• Collaborate with physician-scientists to translate clinical requirements into computational solutions.
• Contribute to peer-reviewed manuscripts and present findings.

Skills

Python

R

Bash

Linux/HPC

Genomics/Bioinformatics

Data analysis

Team collaboration

Education

PhD in Genetics/Genomics/Computational Biology

Bachelor's degree

Tools

Variant annotation tools

Linux/Unix HPC

Job description

Boston Children's Hospital is seeking a Genomic Scientist to lead integrative analyses of RNA sequencing, methylation, long-read sequencing, and WGS/WES data in a translational pediatric context.

You will develop pipelines, apply variant interpretation algorithms, and collaborate with physician-scientists to turn clinical requirements into computational solutions, contributing to research and clinical care.