Therapeutics Process Development Scientist

Socket.dev; Memphis (TN); On-site; USD 86,000 - 155,000; Full time

Job summary

St. Jude Children's Research Hospital is seeking a Scientist - Development to design and execute process development experiments for both upstream and downstream operations within a GMP setting.

You will perform small-scale cell culture, operate bioreactors for mammalian or bacterial culture, and optimize purification methods using chromatography techniques. The role requires Bachelor's degree with 7+ years of relevant experience; Master's or PhD is preferred.

Qualifications

• Bachelor's degree in a relevant science required.
• Master's or PhD preferred.
• 7+ years experience in GMP/related field.
• Experience with cell culture, bioreactors, and purification techniques.
• Ability to coordinate projects and document results.

Responsibilities

• Coordinate project processes in GMP/ECTL with guidance, including tech transfer & scale-up runs, HPLC/biologic assays, manufacturing of cellular therapeutics.
• Provide inputs regarding revisions to SOPs and/or process flows within area.
• Support development, documentation, and reporting of relevant experimental data (e.g., production batch records, HPLC reports, summary reports for manufacturing campaigns).
• Monitor and document compliance with quality and regulatory requirements; and address deviations.
• Support monitoring and stocking of supplies, calibration, maintenance, troubleshooting, and purchase of equipment within area.
• Instruct other staff in basic techniques, procedures, and systems within area (e.g., operations of cGMP equipment and control software).
• Perform other duties as assigned to meet the goals and objectives of the department and institution.
• Maintains regular and predictable attendance.

Skills

Cell culture

Bioreactors

Protein purification

Chromatography

GMP knowledge

Education

Bachelor's degree

MS or PhD preferred

Tools

HPLC

Filtration systems

Chromatography equipment

Job description

St. Jude Children's Research Hospital is seeking a Scientist - Development to design and execute process development experiments for both upstream and downstream operations within a GMP setting.

You will perform small-scale cell culture, operate bioreactors for mammalian or bacterial culture, and optimize purification methods using chromatography techniques. The role requires Bachelor's degree with 7+ years of relevant experience; Master's or PhD is preferred.